… In the original study, BALB/c mice were immunized with the OVCA-433 cell line isolated
from the ascites fluid of a patient with ovarian serous papillary cystadenocarcinoma [41]. A …

Women who carry a BRCA1 or BRCA2 mutation are at high risk of breast and ovarian
cancer, and may be at moderately increased risk of other cancer types. This review examines …

Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …

Prostate cancer is the most frequently diagnosed cancer in males in developed countries.
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …

Purpose The purposes of this study were to estimate the reduction in risk of ovarian, fallopian
tube, or peritoneal cancer in women with a BRCA1 or BRCA2 mutation after oophorectomy…

Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …

A single founder allele of the CHEK2 gene has been associated with predisposition to breast
and prostate cancer in North America and Europe. The CHEK2 protein participates in the …

Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify additional …

Genome-wide association studies (GWAS) have identified four susceptibility loci for
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome-wide …

Germline BRCA1 mutations predispose to breast cancer. To identify genetic modifiers of this
risk, we performed a genome-wide association study in 1,193 individuals with BRCA1 …