A number of prenatal experiences are associated with adverse outcomes after birth, ranging
from cardiovascular problems to psychiatric disease. Prenatal stress is associated with …

Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide
association study of 41,917 bipolar disorder cases and 371,549 controls of European …

Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …

Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology.
Understanding the genetic factors contributing to the shared and disorder-specific symptoms …

Exposure to chronic stress, either repeated severe acute or moderate sustained stress, is
one of the strongest risk factors for the development of psychopathologies such as post-…

Background Lithium is a first-line treatment in bipolar disorder, but individual response is
variable. Previous studies have suggested that lithium response is a heritable trait. However, …

… The thermal cycling conditions were set as follows: 50 C for 2 min, 95 C for 10 min, 40
cycles each of 95 C for 15 s and 60 C for 60 s. The cycle threshold (CT) values for all replicates …

Major depressive disorder (MDD) is a prevalent mood disorder that is associated with
differential prefrontal brain expression patterns 1 . Treatment of MDD includes a variety of …

… The processes extended by reactive microglia were less extensive and generally longer
than the cell body diameter (Figures 2c and 3c), whereas amoeboid microglia were either …

Bipolar disorder (BD) is a genetically complex mental illness characterized by severe
oscillations of mood and behaviour. Genome-wide association studies (GWAS) have identified …