Purpose Glaucoma is the leading cause of global irreversible blindness. Present estimates
of global glaucoma prevalence are not up-to-date and focused mainly on European ancestry …

… The initial search was scrutinised in detail by clinician scientist XS and reviewed by senior
clinician scientist C-YC. Data were checked by statisticians (WLW, XL). Disagreements were …

… MD, PhD 1 2 , Tien Yin Wong MD, PhD 1 2 8 ‡ , Ching-Yu Cheng MD, PhD 1 2 8 ‡ …
Disagreements between the 2 were resolved and adjudicated by the senior author (C.-YC). …

Background One of the global targets for non-communicable diseases is to halt, by 2025,
the rise in the age-standardised adult prevalence of diabetes at its 2010 levels. We aimed to …

Background Underweight, overweight, and obesity in childhood and adolescence are associated
with adverse health consequences throughout the life-course. Our aim was to estimate …

Abstract Treatment of pediatric acute lymphoblastic leukemia (ALL) is based on the concept
of tailoring the intensity of therapy to a patient's risk of relapse. To determine whether gene …

Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy
of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases …

… Then the furnace temperature is ramped to 800 C at a rate of 39 C min −1 and the deposition
of monolayer WS 2 crystals is implemented at 800 C for 5 min with 50 sccm of Ar carrier gas…

Background Raised blood pressure is an important risk factor for cardiovascular diseases
and chronic kidney disease. We estimated worldwide trends in mean systolic and mean …

Background Despite best current therapy, up to 20% of pediatric patients with acute lymphoblastic
leukemia (ALL) have a relapse. Recent genomewide analyses have identified a high …