User profiles for C. Birger

Chet B Birger

- Verified email at broadinstitute.org - Cited by 13551

Charles Burger

- Verified email at mayo.edu - Cited by 7629

[PDF][PDF] Proteogenomic data and resources for pan-cancer analysis

…, AP Calinawan, F Aguet, Y Akiyama, S Anand, C Birger… - Cancer cell, 2023 - cell.com
The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium (CPTAC)
investigates tumors from a proteogenomic perspective, creating rich multi-omics datasets …

[PDF][PDF] The molecular signatures database hallmark gene set collection

A Liberzon, C Birger, H Thorvaldsdóttir, M Ghandi… - Cell systems, 2015 - cell.com
… square N by N matrix 𝑪 that contains the cardinalities of the intersection of every pair of …
where B is a square matrix where all columns are identical and correspond to the diagonal of 𝑪. …

[PDF][PDF] Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma

…, B Hindenach, B Pruetz, B Kubisa, BJ Druker, C Birger… - Cell, 2020 - cell.com
To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and …

Toil enables reproducible, open source, big biomedical data analyses

…, M Cline, B O'Connor, M Hanna, C Birger… - Nature …, 2017 - nature.com
9.128 (Jones and Bartlett Publishers, 2006). 6. Storch, M. et al. BASIC: a new biopart assembly
standard for idempotent cloning provides accurate, singletier DNA assembly for synthetic …

[PDF][PDF] Proteogenomic characterization of pancreatic ductal adenocarcinoma

…, H Zhang, M Amin, E An, C Ayad, T Bauer, C Birger… - Cell, 2021 - cell.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …

Genetic and transcriptional evolution alters cancer cell line drug response

…, A Tsherniak, F Vazquez, B Wong, C Birger… - Nature, 2018 - nature.com
… ΔT))/(log(c 2 ) − log(c 1 )), in which c 1 and c 2 were the minimum and maximum percentage
… , and ΔT was the time elapsed between c 1 and c 2 . To account for potential differences in …

[PDF][PDF] A proteogenomic portrait of lung squamous cell carcinoma

…, BJ Druker, C Huynh, CA Goldthwaite, C Birger… - Cell, 2021 - cell.com
Lung squamous cell carcinoma (LSCC) remains a leading cause of cancer death with few
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …

Acute mesenteric ischemia: a clinical review

…, TJ Rodenberg, HJ Edmonds, CD Burger - Archives of internal …, 2004 - jamanetwork.com
Acute mesenteric ischemia is a life-threatening vascular emergency that requires early
diagnosis and intervention to adequately restore mesenteric blood flow and to prevent bowel …

[PDF][PDF] Integrated proteogenomic characterization of clear cell renal cell carcinoma

…, BJ Druker, CJ Newton, C Birger, CD Jones, C Tognon… - Cell, 2019 - cell.com
To elucidate the deregulated functional modules that drive clear cell renal cell carcinoma (ccRCC),
we performed comprehensive genomic, epigenomic, transcriptomic, proteomic, and …

Nanofibrous materials and their applications

C Burger, BS Hsiao, B Chu - Annu. Rev. Mater. Res., 2006 - annualreviews.org
… The air inlet block was made of high-performance polyetheretherketone (PEEK, for electrical
insulation) and could be operated at temperatures as high as 150C. The air gaps could be …