… , In the brain, both glioblastoma and brain metastases oxidize [ 13 C]glucose within the
TCA cycle, can use [ 13 C]acetate as a TCA cycle fuel and synthesize glutamine from either …

Blocking Programmed Death–1 (PD-1) can reinvigorate exhausted CD8 T cells (T EX ) and
improve control of chronic infections and cancer. However, whether blocking PD-1 can …

… 13 C) are stable but approximately 1 dalton heavier and thus readily distinguished by mass
spectrometry; 13 C’… For 13 C and 15 N stable isotope tracers, we have found that a circulating …

… c, The concentration of diaphragm and quadriceps muscle [1- 13 C]2-deoxyglucose phosphate
versus the integral of blood [1- 13 C]2-deoxglucose with respect to time during [1- 13 C]2-…

Mammalian genes transcribe RNA not continuously, but in bursts. Transcriptional output can
be modulated by altering burst fraction or burst size, but how regulatory elements control …

… (C) Comparison between the average dietary flux and fasted circulatory turnover flux, here
… Autosampler temperature was 5 C, column temperature was 60 C and injection volume was …

… (C and D) Labeling in serum glucose and lactate and tissue glycolytic intermediates
normalized to glycogen labeling in the liver (C) or the quadriceps (D) at the end of the pulse-chase …

Bromodomain and extraterminal motif (BET) proteins are pharmacologic targets for the treatment
of diverse diseases, yet the roles of individual BET family members remain unclear. We …

Transcriptional regulation occurs via changes to rates of different biochemical steps of
transcription, but it remains unclear which rates are subject to change upon biological perturbation…

… (C) In cells subjected to nocodazole arrest–release and … (D) From the same experiment
as in C, we show the … of the transcriptional spike as shown in C. Horizontal dotted lines mark …