Bladder cancer is a heterogeneous group of tumours with at least 40 histological subgroups.
Patients with localized disease can be cured with surgical resection or radiotherapy, but …

Intercellular communication sets the pace for transformed cells to survive and to thrive.
Extracellular vesicles (EVs), such as exosomes, microvesicles and large oncosomes, are …

Langerhans cell histiocytosis (LCH) has been previously thought of as a rare illness, but is
now increasingly diagnosed as a result of the more intensive investigations of patients with …

Circulating tumor-derived DNA (ctDNA) can be used to monitor cancer dynamics noninvasively.
Detection of ctDNA can be challenging in patients with low-volume or residual disease, …

Purpose Patients with high-risk (International Federation of Gynecology and Obstetrics score
7) gestational trophoblastic neoplasia (GTN) frequently receive etoposide, methotrexate, …

A major challenge in cancer genetics is to determine which low-frequency somatic mutations
are drivers of tumorigenesis. Here we interrogate the genomes of 7,651 diverse human …

… (C) Number of tumors developed in the cohort of 4-OHT–treated BCTSB13 mice; 70% of the
mice developed more than one tumor. (D) Melanomas of 4-OHT–treated BCTSB13 mice first …

Castration-resistant prostate cancer (CRPC) is the major cause of death from prostate
cancer. Biomarkers to improve early detection and prediction of CRPC especially using non-…

… (C) The sensitivity to trametinib of NF1 negative melanoma cell lines is comparable to
those that express NF1. Data are graphed as in A. (D) Treatment with trametinib at escalating …

Purpose To describe and compare differences in peri-operative outcomes of robot-assisted (RA-RPLND)
and open (O-RPLND) retroperitoneal lymph node dissection performed by a …