User profiles for C. T. Gross

Cornelius Gross

EMBL
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Cited by 20770

The many paths to fear

CT Gross, NS Canteras - Nature Reviews Neuroscience, 2012 - nature.com
Fear is an emotion that has powerful effects on behaviour and physiology across animal
species. It is accepted that the amygdala has a central role in processing fear. However, it is …

Errant gardeners: glial-cell-dependent synaptic pruning and neurodevelopmental disorders

U Neniskyte, CT Gross - Nature Reviews Neuroscience, 2017 - nature.com
The final stage of brain development is associated with the generation and maturation of
neuronal synapses. However, the same period is also associated with a peak in synapse …

The neural circuits of innate fear: detection, integration, action, and memorization

BA Silva, CT Gross, J Gräff - Learning & memory, 2016 - learnmem.cshlp.org
How fear is represented in the brain has generated a lot of research attention, not only because
fear increases the chances for survival when appropriately expressed but also because …

Synaptic pruning by microglia is necessary for normal brain development

…, E Guiducci, L Dumas, D Ragozzino, CT Gross - science, 2011 - science.org
Microglia are highly motile phagocytic cells that infiltrate and take up residence in the
developing brain, where they are thought to provide a surveillance and scavenging function. …

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

…, A Bifone, A Gozzi, D Ragozzino, CT Gross - Nature …, 2014 - nature.com
… The reduced synaptic multiplicity seen in Cx3cr1 KO mice suggested that gross connectivity
between brain regions might be weakened. To quantify long-range functional connectivity, …

[HTML][HTML] Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

…, A Raggioli, A Schertel, Y Schwab, CT Gross - Nature …, 2018 - nature.com
Microglia are highly motile glial cells that are proposed to mediate synaptic pruning during
neuronal circuit formation. Disruption of signaling between microglia and neurons leads to an …

Independent hypothalamic circuits for social and predator fear

…, NS Canteras, D Ragozzino, CT Gross - Nature …, 2013 - nature.com
The neural circuits mediating fear to naturalistic threats are poorly understood. We found
that functionally independent populations of neurons in the ventromedial hypothalamus (VMH), …

[PDF][PDF] A neural switch for active and passive fear

…, AJ Schwarz, T Tsetsenis, D Ragozzino, CT Gross… - Neuron, 2010 - cell.com
The central nucleus of the amygdala (CeA) serves as a major output of this structure and
plays a critical role in the expression of conditioned fear. By combining cell- and tissue-specific …

[HTML][HTML] Prefrontal cortical control of a brainstem social behavior circuit

…, A Illarionova, V Grinevich, T Branco, CT Gross - Nature …, 2017 - nature.com
The prefrontal cortex helps adjust an organism's behavior to its environment. In particular,
numerous studies have implicated the prefrontal cortex in the control of social behavior, but …

[HTML][HTML] High-resolution structural and functional deep brain imaging using adaptive optics three-photon microscopy

…, M Barbieri, R Rehm, S Deivasigamani, CT Gross… - Nature …, 2021 - nature.com
Multiphoton microscopy has become a powerful tool with which to visualize the morphology
and function of neural cells and circuits in the intact mammalian brain. However, tissue …