… Wolf, BS 1 ; Helen Y. Chu, MD, MPH 1 … Concept and design: Logue, Franko, McCulloch,
Magedson, Wolf, Chu. …

Studies of low basal Jun N‐terminal kinase (JNK) activity in non‐stressed cells led us to
identify a JNK inhibitor that was purified and identified as glutathione S‐transferase Pi (GSTp) …

Two variant glutathione S-transferase cDNAs have been described at the GSTP1 locus, which
differ by a single base pair (AG) substitution at nucleotide 313 of the GSTP1 cDNA. This …

Northern blotting has shown that mouse small intestine contains relatively large amounts of
the nuclear factor-E2 p45-related factor (Nrf) 2 transcription factor but relatively little Nrf1. …

Colorectal cancer is one of the most significant causes of cancer death. A genetic model for
colorectal cancer has been proposed in which the sequential accumulation of mutations in …

SARS-CoV-2 enters cells using its Spike protein, which is also the main target of
neutralizing antibodies. Therefore, assays to measure how antibodies and sera affect Spike-mediated …

Mice that lack the Nrf2 basic-region leucine-zipper transcription factor are more sensitive
than wild-type (WT) animals to the cytotoxic and genotoxic effects of foreign chemicals and …

… Burke MD and Wolf CR, Substrates and inhibitors as probes of individual forms of drug …
Miles JS, Skett P and Wolf CR. Relative expression of cytochrome P450 isoenzymes in human …

To standardize CYP2D6 allele nomenclature, and to conform with international human gene
nomenclature guidelines, an alternative to the current arbitrary system is described. Based …

Mammalian cytosolic glutathione S-transferases (GSTs; EC 2.5.1.18) form a supergene family
consisting of four distinct families, named alpha, mu, pi and theta. In humans one member …