User profiles for C. P. Hersh
Craig HershBrigham and Women's Hospital Verified email at channing.harvard.edu Cited by 14225 |
Chronic obstructive pulmonary disease in α1-antitrypsin PI MZ heterozygotes: a meta-analysis
Background: Severe α 1 -antitrypsin deficiency, usually related to homozygosity for the
protease inhibitor (PI) Z allele, is a proven genetic risk factor for chronic obstructive pulmonary …
protease inhibitor (PI) Z allele, is a proven genetic risk factor for chronic obstructive pulmonary …
The COPD genetic association compendium: a comprehensive online database of COPD genetic associations
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide. COPD is thought to arise from the interaction of environmental exposures and …
worldwide. COPD is thought to arise from the interaction of environmental exposures and …
The protease inhibitor PI* S allele and COPD: a meta-analysis
In many countries, the protease inhibitor (SERPINA1) PI*S allele is more common than PI*Z,
the allele responsible for most cases of chronic obstructive pulmonary disease (COPD) due …
the allele responsible for most cases of chronic obstructive pulmonary disease (COPD) due …
[HTML][HTML] A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci
There is considerable variability in the susceptibility of smokers to develop chronic obstructive
pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α 1 -…
pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α 1 -…
[HTML][HTML] The clinical features of the overlap between COPD and asthma
Background The coexistence of COPD and asthma is widely recognized but has not been
well described. This study characterizes clinical features, spirometry, and chest CT scans of …
well described. This study characterizes clinical features, spirometry, and chest CT scans of …
[HTML][HTML] MMP12, Lung Function, and COPD in High-Risk Populations
Background Genetic variants influencing lung function in children and adults may ultimately
lead to the development of chronic obstructive pulmonary disease (COPD), particularly in …
lead to the development of chronic obstructive pulmonary disease (COPD), particularly in …
Variants in FAM13A are associated with chronic obstructive pulmonary disease
…, BJ Klanderman, JS Sylvia, JP Ziniti, CP Hersh… - Nature …, 2010 - nature.com
We performed a genome-wide association study for chronic obstructive pulmonary disease (COPD)
in three population cohorts, including 2,940 cases and 1,380 controls who were …
in three population cohorts, including 2,940 cases and 1,380 controls who were …
The chronic bronchitic phenotype of COPD: an analysis of the COPDGene Study
…, BJ Make, JD Newell, JE Hokanson, CP Hersh… - Chest, 2011 - Elsevier
… Ms Vance, Drs Hokanson and Hersh, and Mr Stinson have reported that no potential
conflicts of interest exist with any companies/organizations whose products or services may be …
conflicts of interest exist with any companies/organizations whose products or services may be …
Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis
…, M Mattheisen, PJ Castaldi, CP Hersh… - The lancet Respiratory …, 2014 - thelancet.com
Background The genetic risk factors for susceptibility to chronic obstructive pulmonary disease
(COPD) are still largely unknown. Additional genetic variants are likely to be identified by …
(COPD) are still largely unknown. Additional genetic variants are likely to be identified by …
The clinical and genetic features of COPD-asthma overlap syndrome
Individuals with chronic obstructive pulmonary disease (COPD) and asthma are an important
but poorly characterised group. The genetic determinants of COPD and asthma overlap …
but poorly characterised group. The genetic determinants of COPD and asthma overlap …