Spinal muscular atrophy is one of the most common inherited forms of neurological disease
leading to infant mortality. Patients have selective loss of lower motor neurons resulting in …

SMN1 and SMN2 (survival motor neuron) encode identical proteins. A critical question is
why only the homozygous loss of SMN1, and not SMN2, results in spinal muscular atrophy (…

Spinal muscular atrophy (SMA) is a recessive disorder characterized by loss of motor neurons
in the spinal cord. It is caused by mutations in the telomeric survival motor neuron 1 (SMN1…

Spinal muscular atrophy (SMA) is a motor-neuron disorder resulting from anterior-horn–cell
death. The autosomal recessive form has a carrier frequency of 1 in 50 and is the most …

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been rapidly
evolving in the form of new variants. At least eleven known variants have been reported. The …

The survival motor neuron genes, SMN1 and SMN2, encode identical proteins; however, only
homo‐ zygous loss of SMN1 correlates with the development of spinal muscular atrophy (…

Spinal muscular atrophy (SMA), a common motor neuron disease in humans, results from
loss of functional survival motor neuron (SMN1) alleles. A nearly identical copy of the gene, …

Spinal muscular atrophy ( SMA ) is an autosomal recessive disorder that is the leading genetic
cause of infantile death. SMA is characterized by loss of motor neurons in the ventral horn …

… Lorson, Hansjorg Rindt, Monir Shababi, Spinal muscular atrophy: mechanisms and therapeutic
strategies… We would like to thank members of the Lorson Lab for their helpful discussions. …

Spinal muscular atrophy (SMA) is an autosomal recessive disorder, which is the leading
genetic cause of infantile death. SMA is the most common inherited motor neuron disease and …