Extracting biologically meaningful information from the continuing flood of genomic data is a
major challenge in the life sciences. Codon usage bias (CUB) is a general feature of most …

… To the Graduate Council: I am submitting herewith a dissertation written by Cedric Lars
Landerer entitled "Application of mechanistic models to separate the effects of mutation, selection…

Errors in protein translation can lead to non-genetic, phenotypic mutations, including amino
acid misincorporations. While phenotypic mutations can increase protein diversity, the …

… CL and MAG initiated the study. CL collected and analyzed the data and wrote the … of
introgression from codons in Lachancea kluveri using a mutation-selection model by Landerer et al. …

Errors in protein synthesis can lead to non-genetic phenotypic mutations, which contribute
to generating a wide range of protein diversity. There are currently no methods to measure …

The global seasonal cycle of energy in Earth’s climate system is quantified using observations
and reanalyses. After removing long-term trends, net energy entering and exiting the …

The Sec secretion pathway is found across all domains of life. A critical feature of Sec secreted
proteins is the signal peptide, a short peptide with distinct physicochemical properties …

AnaCoDa is an R package for estimating biologically relevant parameters of mixture models,
such as selection against translation inefficiency, non-sense errors and ribosome pausing …

After enhancing the power conversion efficiencies of organic solar cells beyond 10%, their
long term stability has become the most urgent challenge in order to eventually integrate …

The regional variability of sea level is an integral indicator of changing oceanographic
conditions due to different processes of oceanic, atmospheric, and terrestrial origin. The present …