User profiles for C. K. Yinda
 | Claude Kwe YindaNIAID/NIH Verified email at nih.gov Cited by 5259 |
[HTML][HTML] Ecology, evolution and spillover of coronaviruses from bats
In the past two decades, three coronaviruses with ancestral origins in bats have emerged
and caused widespread outbreaks in humans, including severe acute respiratory syndrome …
and caused widespread outbreaks in humans, including severe acute respiratory syndrome …
[HTML][HTML] SARS-CoV-2 infection and persistence in the human body and brain at autopsy
Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction 1 , 2 – 3
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), …
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), …
[HTML][HTML] Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2
…, J Schulz, N Van Doremalen, I Leighton, CK Yinda… - Nature, 2020 - nature.com
Effective therapies to treat coronavirus disease 2019 (COVID-19) are urgently needed. While
many investigational, approved, and repurposed drugs have been suggested as potential …
many investigational, approved, and repurposed drugs have been suggested as potential …
Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces viral shedding after SARS-CoV-2 D614G challenge in preclinical models
ChAdOx1 nCoV-19/AZD1222 is an approved adenovirus-based vaccine for severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being deployed globally. Previous …
respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being deployed globally. Previous …
[HTML][HTML] Effectiveness of N95 respirator decontamination and reuse against SARS-CoV-2 virus
The coronavirus pandemic has created worldwide shortages of N95 respirators. We analyzed
4 decontamination methods for effectiveness in deactivating severe acute respiratory …
4 decontamination methods for effectiveness in deactivating severe acute respiratory …
[HTML][HTML] Modular approach to customise sample preparation procedures for viral metagenomics: a reproducible protocol for virome analysis
A major limitation for better understanding the role of the human gut virome in health and
disease is the lack of validated methods that allow high throughput virome analysis. To …
disease is the lack of validated methods that allow high throughput virome analysis. To …
[HTML][HTML] K18-hACE2 mice develop respiratory disease resembling severe COVID-19
SARS-CoV-2 emerged in late 2019 and resulted in the ongoing COVID-19 pandemic.
Several animal models have been rapidly developed that recapitulate the asymptomatic to …
Several animal models have been rapidly developed that recapitulate the asymptomatic to …
[HTML][HTML] Effect of environmental conditions on SARS-CoV-2 stability in human nasal mucus and sputum
We found that environmental conditions affect the stability of severe acute respiratory
syndrome coronavirus 2 in nasal mucus and sputum. The virus is more stable at low-temperature …
syndrome coronavirus 2 in nasal mucus and sputum. The virus is more stable at low-temperature …
SARS-CoV-2 infection and persistence throughout the human body and brain
COVID-19 is known to cause multi-organ dysfunction 1-3 in acute infection, with prolonged
symptoms experienced by some patients, termed Post-Acute Sequelae of SARS-CoV-2 (…
symptoms experienced by some patients, termed Post-Acute Sequelae of SARS-CoV-2 (…
[HTML][HTML] SARS-CoV-2 disease severity and transmission efficiency is increased for airborne compared to fomite exposure in Syrian hamsters
Transmission of SARS-CoV-2 is driven by contact, fomite, and airborne transmission. The
relative contribution of different transmission routes remains subject to debate. Here, we show …
relative contribution of different transmission routes remains subject to debate. Here, we show …