Meiosis is one of the defining events in gametogenesis. Male and female germ cells both
undergo one round of meiotic cell division during their development in order to reduce the …

The human genome contains more than 4.5 million inserts derived from transposable
elements (TEs), the result of recurrent waves of invasion and internal propagation throughout …

Meiosis is a key event in gametogenesis that generates new combinations of genetic
information and is required to reduce the chromosome content of the gametes. Meiotic …

10.7554/eLife.26152.001 Mobilization of retrotransposons to new genomic locations is a
significant driver of mammalian genome evolution, but these mutagenic events can also cause …

Transposable elements (TEs) account for more than 50% of the human genome and many
have been co-opted throughout evolution to provide regulatory functions for gene expression …

Meiosis relies on the SPO11 endonuclease to generate the recombinogenic DNA double
strand breaks (DSBs) required for homologous chromosome synapsis and segregation. The …

… Christopher Playfoot is the first author of this paper, “Transposable elements contribute to
the spatiotemporal microRNA landscape in human brain development.” Christopher did this …

Transposable element (TE) silencing is initiated early in mammalian development and
maintained during somatic differentiation. Reporting in this issue of Developmental Cell, Ecco et al…

Meiosis relies on the SPO11 endonuclease to generate the recombinogenic DNA double
strand breaks (DSBs) required for homologous chromosome synapsis and segregation. The …

Mobilisation of retrotransposons to new genomic locations is a significant driver of mammalian
genome evolution. In humans, retrotransposon mobilisation is mediated primarily by …