… This question has been studied theoretically by Charlesworth & Langley (31). They concluded
that, if … Langley, CH 1 989. Reduced variation in the yellow-achaete-scute region in natural …

Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

The number of selectively neutral polymorphic sites in a random sample of genes can be
affected by ancestral selectively favored substitutions at linked loci. The degree to which this …

Existing human genome assemblies have almost entirely excluded repetitive sequences
within and near centromeres, limiting our understanding of their organization, evolution, and …

The population genetic perspective is that the processes shaping genomic variation can be
revealed only through simultaneous investigation of sequence polymorphism and …

The level of DNA sequence variation is reduced in regions of the Drosophila melanogaster
genome where the rate of crossing over per physical distance is also reduced. This …

Various possible models of carcinogenesis are analyzed with respect to low dose kinetics.
The importance of background carcinogenesis upon the shape of the dose-response curve at …

Background The size and complexity of conifer genomes has, until now, prevented full genome
sequencing and assembly. The large research community and economic importance of …

… These findings are consistent with our preliminary results reported previously (Langley
and … Previously we (Langley and Fitch, 1973) utilized a simple goodness of fit Z analysis: (…

The statistical power of five association study test statistics (two haplotype-based tests, two
marker-based tests, and the Transmission Disequilibrium Test–Q5) to detect single …