User profiles for C. G. Knight
Chris KnightUniversity of Manchester Verified email at manchester.ac.uk Cited by 2809 |
Harnessing rhizosphere microbiomes for drought-resilient crop production
Root-associated microbes can improve plant growth, and they offer the potential to increase
crop resilience to future drought. Although our understanding of the complex feedbacks …
crop resilience to future drought. Although our understanding of the complex feedbacks …
L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L
…, MA Brown, H Kirschke, CG Knight… - Biochemical …, 1982 - portlandpress.com
1. L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) at a concentration of 0.5
mM had no effect on the serine proteinases plasma kallikrein and leucocyte elastase or the …
mM had no effect on the serine proteinases plasma kallikrein and leucocyte elastase or the …
[HTML][HTML] Structural basis of collagen recognition by integrin α2β1
J Emsley, CG Knight, RW Farndale, MJ Barnes… - Cell, 2000 - cell.com
We have determined the crystal structure of a complex between the I domain of integrin α2β1
and a triple helical collagen peptide containing a critical GFOGER motif. Three loops on the …
and a triple helical collagen peptide containing a critical GFOGER motif. Three loops on the …
[HTML][HTML] The Collagen-binding A-domains of Integrins α1β1 and α2β1recognize the same specific amino acid sequence, GFOGER, in native (Triple-helical) collagens
CG Knight, LF Morton, AR Peachey… - Journal of Biological …, 2000 - ASBMB
We have previously assigned an integrin α 2 β 1 -recognition site in collagen I to the
sequence, GFOGERGVEGPOGPA (O = Hyp), corresponding to residues 502–516 of the α 1 (I) …
sequence, GFOGERGVEGPOGPA (O = Hyp), corresponding to residues 502–516 of the α 1 (I) …
A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases
CG Knight, F Willenbrock, G Murphy - FEBS letters, 1992 - Elsevier
(7-methoxycoumarin-4-yl)Acetyl-Pro-Leu-Gly-Leu-(3-[2,4-dinitrophenyl]-l-2,3-diaminopropionyl)-Ala-Arg-NH
2 (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH 2 ) has been synthesised as a …
2 (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH 2 ) has been synthesised as a …
[HTML][HTML] TNF-α converting enzyme (TACE) is inhibited by TIMP-3
…, PM Slocombe, A Webster, M Butler, CG Knight… - FEBS letters, 1998 - Elsevier
TNF-α converting enzyme (TACE; ADAM-17) is a membrane-bound disintegrin
metalloproteinase that processes the membrane-associated cytokine proTNF-α to a soluble form. …
metalloproteinase that processes the membrane-associated cytokine proTNF-α to a soluble form. …
Xanthene-dye-labelled phosphatidylethanolamines as probes of interfacial pH. Studies in phospholipid vesicles
CG Knight, T Stephens - Biochemical Journal, 1989 - portlandpress.com
We have been developing the use of plasma-membrane-bound fluorescent probes to measure
the pH values at the surfaces of living chondrocytes. For this purpose, three lipophilic pH …
the pH values at the surfaces of living chondrocytes. For this purpose, three lipophilic pH …
The collagen-platelet interaction
MJ Barnes, CG Knight… - Current opinion in …, 1998 - journals.lww.com
Collagen-platelet interaction, occurring in hemostasis but also a cause of thrombosis, is a
two-step process of adhesion and activation involving the sequential recognition of distinct …
two-step process of adhesion and activation involving the sequential recognition of distinct …
[HTML][HTML] The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3
A Amour, CG Knight, A Webster, PM Slocombe… - FEBS letters, 2000 - Elsevier
A recombinant soluble form of the catalytic domain of human ADAM-10 was expressed as
an Fc fusion protein from myeloma cells. The ADAM-10 was catalytically active, cleaving …
an Fc fusion protein from myeloma cells. The ADAM-10 was catalytically active, cleaving …
[HTML][HTML] Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens
Background Pseudomonas fluorescens are common soil bacteria that can improve plant
health through nutrient cycling, pathogen antagonism and induction of plant defenses. The …
health through nutrient cycling, pathogen antagonism and induction of plant defenses. The …