The gastrointestinal microbiome is a complex ecosystem with functions that shape human
health. Studying the relationship between taxonomic alterations and functional repercussions …

Perturbations to the colonization process of the human gastrointestinal tract have been
suggested to result in adverse health effects later in life. Although much research has been …

Background Metagenomics is limited in its ability to link distinct microbial populations to
genetic potential due to a current lack of representative isolate genome sequences. Reference-…

Background Pathogenic microorganisms cause disease by invading, colonizing, and
damaging their host. Virulence factors including bacterial toxins contribute to pathogenicity. …

Existing workflows for the analysis of multi-omic microbiome datasets are lab-specific and
often result in sub-optimal data usage. Here we present IMP, a reproducible and modular …

The development of reliable, mixed-culture biotechnological processes hinges on
understanding how microbial ecosystems respond to disturbances. Here we reveal extensive …

Background: Mixed microbial communities underpin important biotechnological processes
such as biological wastewater treatment (BWWT). A detailed knowledge of community …

The human gut microbiome produces a functional complex of biomolecules, including
nucleic acids, (poly)peptides, structural molecules, and metabolites. This impacts human …

Metagenomics-based studies of mixed microbial communities are impacting biotechnology,
life sciences and medicine. Computational binning of metagenomic data is a powerful …

Microbial communities are complex and dynamic systems that are primarily structured
according to their members’ ecological niches. To investigate how niche breadth (generalist …