User profiles for C. B. Vagbo
 | Cathrine Broberg VågbøDr. philos, Norwegian University of Science and Technology Verified email at ntnu.no Cited by 8637 |
[PDF][PDF] ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility
N 6 -methyladenosine (m 6 A) is the most prevalent internal modification of messenger RNA
(mRNA) in higher eukaryotes. Here we report ALKBH5 as another mammalian demethylase …
(mRNA) in higher eukaryotes. Here we report ALKBH5 as another mammalian demethylase …
A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
We adapted UV CLIP (cross-linking immunoprecipitation) to accurately locate tens of thousands
of m 6 A residues in mammalian mRNA with single-nucleotide resolution. More than 70…
of m 6 A residues in mammalian mRNA with single-nucleotide resolution. More than 70…
Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational …
…, E van den Born, V Leihne, CB Vågbø… - … and cellular biology, 2010 - Am Soc Microbiol
Uridines in the wobble position of tRNA are almost invariably modified. Modifications can
increase the efficiency of codon reading, but they also prevent mistranslation by limiting …
increase the efficiency of codon reading, but they also prevent mistranslation by limiting …
[HTML][HTML] Biochemical reconstitution of TET1–TDG–BER-dependent active DNA demethylation reveals a highly coordinated mechanism
…, AB Robertson, A Kuśnierczyk, CB Vågbø… - Nature …, 2016 - nature.com
Cytosine methylation in CpG dinucleotides is an epigenetic DNA modification dynamically
established and maintained by DNA methyltransferases and demethylases. Molecular …
established and maintained by DNA methyltransferases and demethylases. Molecular …
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA
J Ringvoll, LM Nordstrand, CB Vågbø, V Talstad… - The EMBO …, 2006 - embopress.org
Two human homologs of the Escherichia coli AlkB protein, denoted hABH2 and hABH3,
were recently shown to directly reverse 1‐methyladenine (1meA) and 3‐methylcytosine (3meC) …
were recently shown to directly reverse 1‐methyladenine (1meA) and 3‐methylcytosine (3meC) …
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage
Methylating agents are ubiquitous in the environment, and central in cancer therapy. The 1‐methyladenine
and 3‐methylcytosine lesions in DNA/RNA contribute to the cytotoxicity of …
and 3‐methylcytosine lesions in DNA/RNA contribute to the cytotoxicity of …
Hepatitis C virus RNA is 5′-capped with flavin adenine dinucleotide
RNA viruses have evolved elaborate strategies to protect their genomes, including 5′
capping. However, until now no RNA 5′ cap has been identified for hepatitis C virus 1 , 2 (HCV), …
capping. However, until now no RNA 5′ cap has been identified for hepatitis C virus 1 , 2 (HCV), …
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA
RNA methylations are essential both for RNA structure and function, and are introduced by a
number of distinct methyltransferases (MTases). In recent years, N 6 -methyladenosine (m 6 …
number of distinct methyltransferases (MTases). In recent years, N 6 -methyladenosine (m 6 …
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA
Repair of DNA damage is essential for maintaining genome integrity, and repair deficiencies
in mammals are associated with cancer, neurological disease and developmental defects 1 …
in mammals are associated with cancer, neurological disease and developmental defects 1 …
[PDF][PDF] The mammalian cap-specific m6Am RNA methyltransferase PCIF1 regulates transcript levels in mouse tissues
…, A Roithova, KM Chen, L Li, G Franco, CB Vågbø… - Cell reports, 2020 - cell.com
The 5′ end of eukaryotic mRNAs is protected by the m 7 G-cap structure. The transcription
start site nucleotide is ribose methylated (Nm) in many eukaryotes, whereas an adenosine at …
start site nucleotide is ribose methylated (Nm) in many eukaryotes, whereas an adenosine at …