The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans
…, DJ Friedman, GW Nelson, CA Winkler… - Journal of the …, 2010 - journals.lww.com
Mapping by admixture linkage disequilibrium (LD) detected strong association between
nonmuscle myosin heavy chain 9 gene (MYH9) variants on chromosome 22 and nondiabetic …
nonmuscle myosin heavy chain 9 gene (MYH9) variants on chromosome 22 and nondiabetic …
Admixture mapping comes of age
CA Winkler, GW Nelson… - Annual review of genomics …, 2010 - annualreviews.org
… In a survey of ancestry estimates of Latino populations from California (Los Angeles),
Mexico, Brazil, and Columbia, the Latino populations from Mexico and Los Angeles had …
Mexico, Brazil, and Columbia, the Latino populations from Mexico and Los Angeles had …
HIV-associated nephropathies: epidemiology, pathology, mechanisms and treatment
AZ Rosenberg, S Naicker, CA Winkler… - Nature Reviews …, 2015 - nature.com
HIV is a highly adaptive, rapidly evolving virus, which is associated with renal diseases
including collapsing glomerulopathy—the classic histomorphological form of HIV-associated …
including collapsing glomerulopathy—the classic histomorphological form of HIV-associated …
Association of trypanolytic ApoL1 variants with kidney disease in African Americans
…, PJ Hicks, GW Nelson, B Vanhollebeke, CA Winkler… - Science, 2010 - science.org
African Americans have higher rates of kidney disease than European Americans. Here, we
show that, in African Americans, focal segmental glomerulosclerosis (FSGS) and …
show that, in African Americans, focal segmental glomerulosclerosis (FSGS) and …
The Simons genome diversity project: 300 genomes from 142 diverse populations
Here we report the Simons Genome Diversity Project data set: high quality genomes from 300
individuals from 142 diverse populations. These genomes include at least 5.8 million base …
individuals from 142 diverse populations. These genomes include at least 5.8 million base …
Ancient human genomes suggest three ancestral populations for present-day Europeans
…, R Vasquez, M Villena, M Voevoda, CA Winkler… - Nature, 2014 - nature.com
We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …
Genetic analyses of diverse populations improves discovery for complex traits
… The MEC is a population-based prospective cohort study recruiting men and women from
Hawaii and California, beginning in 1993, and examines lifestyle risk factors and genetic …
Hawaii and California, beginning in 1993, and examines lifestyle risk factors and genetic …
Genetic basis for species vulnerability in the cheetah
A population genetic survey of over 200 structural loci previously revealed that the South
African cheetah (Acinonyx jubatus jubatus) has an extreme paucity of genetic variability, …
African cheetah (Acinonyx jubatus jubatus) has an extreme paucity of genetic variability, …
APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy
Trypanolytic variants in APOL1, which encodes apolipoprotein L1, associate with kidney
disease in African Americans, but whether APOL1-associated glomerular disease has a distinct …
disease in African Americans, but whether APOL1-associated glomerular disease has a distinct …
[HTML][HTML] APOL1 Risk Variants, Race, and Progression of Chronic Kidney Disease
…, BI Freedman, A Ojo, CA Winkler… - … England Journal of …, 2013 - Mass Medical Soc
Background Among patients in the United States with chronic kidney disease, black patients
are at increased risk for end-stage renal disease, as compared with white patients. Methods …
are at increased risk for end-stage renal disease, as compared with white patients. Methods …