Background The domestic pig (Sus scrofa) is important both as a food source and as a
biomedical model given its similarity in size, anatomy, physiology, metabolism, pathology, and …

DFFRY (the Y-linked homologue of the DFFRX Drosophila fat-facets related X gene) maps
to proximal Yq11.2 within the interval defining the AZFa spermatogenic phenotype. The …

The Y chromosome provides a unique opportunity to study mutational processes within the
human genome, decoupled from the confounding effects of interchromosomal recombination. …

Little is known as to why a large number of human diseases are influenced by the major
histocompatibility complex. In some cases, a direct involvement of the products of the …

Protocadherins are members of the cadherin superfamily involved in cell-cell interactions
critical in the development of the central nervous system. This paper describes the isolation, …

We have generated an improved assembly and gene annotation of the pig X Chromosome,
and a first draft assembly of the pig Y Chromosome, by sequencing BAC and fosmid clones …

Background The Y chromosome of mammals is particularly prone to accumulate genes
related to male fertility. However, the high rate of molecular evolution on this chromosome …

The Δ Sxr b deletion interval of the mouse Y chromosome contains Spy , a spermatogenesis
factor gene(s) whose expression is essential for the postnatal development of the mitotic …

Pulsed-field gel electrophoresis and "cosmid walking" have been used to establish a
molecular map of the human major histocompatibility complex (MHC). We have isolated …

… To redress deficiencies and plan appropriate mental health services in South Africa,
reliable epidemiological profiles of psychiatric morbidity are crucial. While few studies of the …