Combinatory antiretroviral therapy (cART) increases the survival and quality of life of HIV-1-infected
patients. However, interruption of therapy almost invariably leads to the re-…

The persistence of latently infected cells in patients under combinatory antiretroviral therapy
(cART) is a major hurdle to HIV-1 eradication. Strategies to purge these reservoirs are …

… marker for strain construction are described in Van Driessche et al. (2005). … B and
phleomycin were purchased from Cayla. For efficient selection, some batches of hygromycin B …

… Upon activation and in the absence of the Tat transactivator (b), the epigenetic
environment of the HIV-1 LTR becomes permissive for transcription, and active NF-kB and P-TEFb …

… Inhibition of NF-kB Activation by Vpu (A and B) 293T cells were transfected with the indicated
vpu alleles as described for Figure 1B using (A) human tetherin or (B) ca IKKb as inducer. …

… As shown in Fig 3B, we observed that the progressively increased times of SAHA treatment
(24, 48 and 72 h) with a constant 72‐h 5‐AzadC treatment were associated with higher HIV …

The positive transcription elongation factor b (P-TEFb) is involved in physiological and
pathological events including inflammation, cancer, AIDS, and cardiac hypertrophy. The balance …

… Several mechanisms operating at the transcriptional level are involved in the
establishment and maintenance of HIV-1 latency, including the absence of crucial inducible …

The one‐step PCR‐mediated technique used for modification of chromosomal loci is a
powerful tool for functional analysis in yeast. Both Saccharomyces cerevisiae and …

Active positive transcription elongation factor b (P-TEFb) is essential for cellular and human
immunodeficiency virus type 1 (HIV-1) transcription elongation. CTIP2 represses P-TEFb …