Microbial communities carry out the majority of the biochemical activity on the planet, and
they play integral roles in processes including metabolism and immune homeostasis in the …

… If system 1 contains 60 instances of A and 30 instances of B, and system 2 contains 900
instances of A and 450 instances of B, these systems would not be classified as different by xipe …

We present the Metagenomic Intra-species Diversity Analysis System (MIDAS), which is an
integrated computational pipeline for quantifying bacterial species abundance and strain-…

Metagenomic studies characterize both the composition and diversity of uncultured viral
and microbial communities. BLAST-based comparisons have typically been used for such …

During the last several decades corals have been in decline and at least one-third of all coral
species are now threatened with extinction. Coral disease has been a major contributor to …

Competition between reef-building corals and benthic algae is of key importance for reef
dynamics. These interactions occur on many spatial scales, ranging from chemical to regional. …

Background Saturated brines are extreme environments of low diversity. Salinibacter ruber
is the only bacterium that inhabits this environment in significant numbers. In order to …

Deep exome resequencing is a powerful approach for delineating patterns of protein-coding
variation among genes, pathways, individuals and populations. We analyzed exome data …

The species composition and metabolic potential of microbial and viral communities are
predictable and stable for most ecosystems. This apparent stability contradicts theoretical …

The coral holobiont is the community of metazoans, protists and microbes associated with
scleractinian corals. Disruptions in these associations have been correlated with coral disease…