User profiles for B. Raught
Brian RaughtSenior Scientist, Princess Margaret Cancer Centre Verified email at uhnres.utoronto.ca Cited by 32192 |
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation
AC Gingras, B Raught… - Annual review of …, 1999 - annualreviews.org
… In mammals, two more distant relatives of eIF4G, p97/novel apolipoprotein B mRNA editing
enzyme (APOBEC) target no. 1 (NAT1)/death-associated protein-5 (DAP-5) and Paip-1 (poly …
enzyme (APOBEC) target no. 1 (NAT1)/death-associated protein-5 (DAP-5) and Paip-1 (poly …
Regulation of translation initiation by FRAP/mTOR
… This compound potently inhibits yeast cell growth, as well as the proliferation of several
types of mammalian cells, including B and T lymphocytes. Rapamycin treatment results in a G 1 …
types of mammalian cells, including B and T lymphocytes. Rapamycin treatment results in a G 1 …
A common open representation of mass spectrometry data and its application to proteomics research
A broad range of mass spectrometers are used in mass spectrometry (MS)-based
proteomics research. Each type of instrument possesses a unique design, data system and …
proteomics research. Each type of instrument possesses a unique design, data system and …
The CRAPome: a contaminant repository for affinity purification–mass spectrometry data
… FC score, FC-B, that is automatically calculated to … FC-B score), it assigned a high probability
to myosins and associated proteins in the ORC2L samples (Fig. 4c). By contrast, the FC-B …
to myosins and associated proteins in the ORC2L samples (Fig. 4c). By contrast, the FC-B …
A global genetic interaction network maps a wiring diagram of cellular function
INTRODUCTION Genetic interactions occur when mutations in two or more genes combine
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
… (B) A representative Western blot showing the levels of the mutants; this Western blot was
… B; the other peptides migrating in this area result from partial chymotryptic cleavage of the …
… B; the other peptides migrating in this area result from partial chymotryptic cleavage of the …
Computational prediction of proteotypic peptides for quantitative proteomics
… Two mixtures, A and B, were constructed. The concentration of each analyte in mixtures A
and B is provided in parenthesis as ([A],[B]). It is evident that some peptides are much more …
and B is provided in parenthesis as ([A],[B]). It is evident that some peptides are much more …
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
… 1A, 2B) were isolated from the maps and identified by capillary liquid chromatography-electrospray
ionization tandem mass spectrometry (LC-MS/MS). The sequence of the …
ionization tandem mass spectrometry (LC-MS/MS). The sequence of the …
A proximity-dependent biotinylation map of a human cell
… to 2% buffer B for 1 min. Next, a linear gradient from 2% to 35% buffer B began eluting the
… from 35 to 80% buffer B over 5 min, and maintaining 80% buffer B for 5 min to elute the …
… from 35 to 80% buffer B over 5 min, and maintaining 80% buffer B for 5 min to elute the …
Analysis of protein complexes using mass spectrometry
… the C subunit is associated with a regulatory protein (B, B′ or B′′; 14 genes in humans)
… subunit (for example, the B subunit) was mutually exclusive to that of another (B′) (A.-CG …
… subunit (for example, the B subunit) was mutually exclusive to that of another (B′) (A.-CG …