Oomycetes form a deep lineage of eukaryotic organisms that includes a large number of
plant pathogens which threaten natural and managed ecosystems. We undertook a survey to …

… A second type of ion in CID is the b ion. These ions start from the N-terminus, and end at
the C terminus of the peptide. Both y and b ions are produced through fragmentation at the …

Oomycetes, or water moulds, are fungal-like organisms phylogenetically related to algae.
They cause devastating diseases in both plants and animals. Here, we describe seven …

Alzheimer's and Parkinson's diseases are associated with the formation in the brain of
amyloid fibrils from β-amyloid and α-synuclein proteins, respectively. It is likely that oligomeric …

How ligand binding alters integrin conformation in outside-in signaling, and how inside-out
signals alter integrin affinity for ligand, have been mysterious. We address this with electron …

… (b) The apparent distribution of sedimentation coefficients of purified A53T protofibrils after
incubation at 4 C for 12 days. (c) Typical electron micrograph area taken from a negatively …

… (b) Gray matter volume only decreased in time in SBPp patients (group × visit, F 6,147 =
3.23, P < 0.01). (c) Whole-brain voxelwise repeated-measures ANOVA for gray matter density …

Pathogens secrete effector proteins and many operate inside plant cells to enable infection.
Some effectors have been found to enter subcellular compartments by mimicking host …

… Images had an isotropic distribution along 60 directions using a b-value of 1000 s/mm 2 .
For each set of diffusion-weighted data, eight volumes with no diffusion weighting were …

… Haustoria (a) and hyphae (b) secrete effectors that are translocated into host cell cytoplasm
by unknown mechanisms. Right panel. Effectors secreted from haustoria (a) and hyphae (…