User profiles for B. P. Lazzaro

Brian P. Lazzaro

Liberty Hyde Bailey Professor, Cornell University; pdfs available at Homepage link below
Verified email at cornell.edu
Cited by 11938

Antimicrobial peptides: Application informed by evolution

BP Lazzaro, M Zasloff, J Rolff - Science, 2020 - science.org
Lazzaro et al. review our knowledge of the evolution and diversity of antimicrobial peptides,
the rapid pharmacodynamics of which make them promising candidates for translational …

Reproduction–immunity trade-offs in insects

RA Schwenke, BP Lazzaro… - Annual review of …, 2016 - annualreviews.org
Immune defense and reproduction are physiologically and energetically demanding
processes and have been observed to trade off in a diversity of female insects. Increased …

Immunity in a variable world

BP Lazzaro, TJ Little - … of the Royal Society B: Biological …, 2009 - royalsocietypublishing.org
… Research in the Lazzaro laboratory is supported by grants from the United States National
Institutes of Health and National Science Foundation. Research in the Little laboratory is …

[HTML][HTML] Evolution of genes and genomes on the Drosophila phylogeny

…, E Lander, CH Langley, R Lapoint, BP Lazzaro… - Nature, 2007 - hal.science
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

Dynamic evolution of the innate immune system in Drosophila

TB Sackton, BP Lazzaro, TA Schlenke, JD Evans… - Nature …, 2007 - nature.com
The availability of complete genome sequence from 12 Drosophila species presents the
opportunity to examine how natural selection has affected patterns of gene family evolution and …

[HTML][HTML] The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster

…, EH Bayne, B Longdon, AH Buck, BP Lazzaro… - PLoS …, 2015 - journals.plos.org
Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …

[HTML][HTML] The evolutionary costs of immunological maintenance and deployment

KA McKean, CP Yourth, BP Lazzaro, AG Clark - BMC evolutionary biology, 2008 - Springer
… Brian P LazzaroLazzaro isolated the P. rettgeri strain used in this experiment from the
hemolymph of a wild-caught D. melanogaster collected near State College, Pennsylvania, USA. …

Genetic Basis of Natural Variation in D. melanogaster Antibacterial Immunity

BP Lazzaro, BK Sceurman, AG Clark - Science, 2004 - science.org
Many genes involved in Drosophila melanogaster innate immune processes have been
identified, but whether naturally occurring polymorphism in these genes leads to variation in …

[HTML][HTML] De Novo Transcriptome Sequencing in Anopheles funestus Using Illumina RNA-Seq Technology

…, A Traoré, KD Vernick, NF Sagnon, BP Lazzaro - PLoS one, 2010 - journals.plos.org
… The trimmed 75 bp and 60 bp paired-end reads were then aligned to the reference final
contig set in BWA, with the maximum number of difference between each read and reference …

Y chromosomal fertility factors kl-2 and kl-3 of Drosophila melanogaster encode dynein heavy chain polypeptides

AB Carvalho, BP Lazzaro… - Proceedings of the …, 2000 - National Acad Sciences
… Furthermore, its repetitive nature does not allow the assembly of the individual sequence
reads (≈500 bp) into larger scaffolds, and these into complete chromosome arms. As a result, …