User profiles for B. L. Elsworth
 | Benjamin ElsworthOur Future Health Verified email at ourfuturehealth.org.uk Cited by 8241 |
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and …
J Zheng, AM Erzurumluoglu, BL Elsworth… - …, 2017 - academic.oup.com
Motivation LD score regression is a reliable and efficient method of using genome-wide
association study (GWAS) summary-level results data to estimate the SNP heritability of complex …
association study (GWAS) summary-level results data to estimate the SNP heritability of complex …
[HTML][HTML] Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
AS Cazet, MN Hui, BL Elsworth, SZ Wu… - Nature …, 2018 - nature.com
The cellular and molecular basis of stromal cell recruitment, activation and crosstalk in
carcinomas is poorly understood, limiting the development of targeted anti-stromal therapies. In …
carcinomas is poorly understood, limiting the development of targeted anti-stromal therapies. In …
Navigating sample overlap, winner's curse and weak instrument bias in Mendelian randomization studies using the UK Biobank
II Sadreev, BL Elsworth, RE Mitchell, L Paternoster… - MedRxiv, 2021 - medrxiv.org
We performed GWAS on 2514 complex traits from the UK Biobank using a linear mixed
model, identifying 40,620 independent significant associations (p<5×10 −8 ). We estimate that …
model, identifying 40,620 independent significant associations (p<5×10 −8 ). We estimate that …
PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics
Background Identifying phenotypic correlations between complex traits and diseases can
provide useful etiological insights. Restricted access to much individual-level phenotype data …
provide useful etiological insights. Restricted access to much individual-level phenotype data …
[PDF][PDF] MRC IEU UK Biobank GWAS pipeline version 1
BL Elsworth, R Mitchell, CA Raistrick… - University of …, 2017 - data.bris.ac.uk
The MRC-IEU UK Biobank genome wide association study (GWAS) pipeline has been
optimized to perform GWAS on the imputed genetic dataset of the full 500 000 from UK Biobank …
optimized to perform GWAS on the imputed genetic dataset of the full 500 000 from UK Biobank …
Using language models and ontology topology to perform semantic mapping of traits between biomedical datasets
Y Liu, BL Elsworth, TR Gaunt - Bioinformatics, 2023 - academic.oup.com
Motivation Human traits are typically represented in both the biomedical literature and large
population studies as descriptive text strings. Whilst a number of ontologies exist, none of …
population studies as descriptive text strings. Whilst a number of ontologies exist, none of …
[CITATION][C] Early Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium. LD Hub: a centralized database and web interface to perform LD score …
J Zheng, AM Erzurumluoglu, BL Elsworth, JP Kemp… - Bioinformatics, 2017
[CITATION][C] MRC IEU UK Biobank GWAS pipeline version 2
R Mitchell, BL Elsworth, R Mitchell, CA Raistrick… - University of Bristol, 2019
[CITATION][C] Early Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium, Pourcain BS, Warrington NM, Finucane HK, Price AL, Bulik-Sullivan BK …
J Zheng, AM Erzurumluoglu, BL Elsworth, JP Kemp… - Bioinformatics (Oxford …, 2017
[CITATION][C] Lifecourse Epidemiology Eczema C, Pourcain BS, Warrington NM, Finucane HK, Price AL, Bulik-Sullivan BK, Anttila V, Paternoster L
J Zheng, AM Erzurumluoglu, BL Elsworth… - 2017 - Gaunt TR, Evans DM, Neale BM. LD …