User profiles for B. J. Pearson
Bret PearsonAssociate Professor, Molecular Genetics, University of Toronto Verified email at utoronto.ca Cited by 4658 |
Recruitment of a hedgehog Regulatory Circuit in Butterfly Eyespot Evolution
DN Keys, DL Lewis, JE Selegue, BJ Pearson… - Science, 1999 - science.org
The origin of new morphological characters is a long-standing problem in evolutionary
biology. Novelties arise through changes in development, but the nature of these changes is …
biology. Novelties arise through changes in development, but the nature of these changes is …
Formaldehyde‐based whole‐mount in situ hybridization method for planarians
BJ Pearson, GT Eisenhoffer, KA Gurley… - Developmental …, 2009 - Wiley Online Library
Whole‐mount in situ hybridization (WISH) is a powerful tool for visualizing gene expression
patterns in specific cell and tissue types. Each model organism presents its own unique set …
patterns in specific cell and tissue types. Each model organism presents its own unique set …
A comparative transcriptomic analysis reveals conserved features of stem cell pluripotency in planarians and mammals
… (BJ Pearson, unpublished data, [35]). In contrast, GSEA revealed that stem cell progeny were
enriched in pathways associated with development, differentiation, as well as several other …
enriched in pathways associated with development, differentiation, as well as several other …
Specification of temporal identity in the developing nervous system
BJ Pearson, CQ Doe - Annu. Rev. Cell Dev. Biol., 2004 - annualreviews.org
▪ Abstract The nervous system of higher organisms exhibits extraordinary cellular diversity
owing to complex spatial and temporal patterning mechanisms. The role of spatial patterning …
owing to complex spatial and temporal patterning mechanisms. The role of spatial patterning …
Regulation of neuroblast competence in Drosophila
BJ Pearson, CQ Doe - Nature, 2003 - nature.com
Individual neural progenitors generate different cell types in a reproducible order in the
retina 1 , 2 , 3 , cerebral cortex 4 , 5 , 6 and probably in the spinal cord 7 . It is unknown how …
retina 1 , 2 , 3 , cerebral cortex 4 , 5 , 6 and probably in the spinal cord 7 . It is unknown how …
A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages
BJ Pearson, AS Alvarado - Development, 2010 - journals.biologists.com
The functions of adult stem cells and tumor suppressor genes are known to intersect. However,
when and how tumor suppressors function in the lineages produced by adult stem cells …
when and how tumor suppressors function in the lineages produced by adult stem cells …
[PDF][PDF] Regulation of temporal identity transitions in Drosophila neuroblasts
Temporal patterning is an important aspect of embryonic development, but the underlying
molecular mechanisms are not well understood. Drosophila neuroblasts are an excellent …
molecular mechanisms are not well understood. Drosophila neuroblasts are an excellent …
The homeobox gene lim-6 is required for distinct chemosensory representations in C. elegans
…, S Faumont, MR Gaston, BJ Pearson… - Nature, 2001 - nature.com
The ability to discriminate between different chemical stimuli is crucial for food detection,
spatial orientation and other adaptive behaviours in animals. In the nematode Caenorhabditis …
spatial orientation and other adaptive behaviours in animals. In the nematode Caenorhabditis …
Coherent control using adaptive learning algorithms
BJ Pearson, JL White, TC Weinacht, PH Bucksbaum - Physical Review A, 2001 - APS
We have constructed an automated learning apparatus to control quantum systems. By
directing intense shaped ultrafast laser pulses into a variety of samples and using a …
directing intense shaped ultrafast laser pulses into a variety of samples and using a …
Genome-wide analysis of the bHLH gene family in planarians identifies factors required for adult neurogenesis and neuronal regeneration
…, SV Nisperos, BN Stanley, BJ Pearson… - …, 2013 - journals.biologists.com
In contrast to most well-studied model organisms, planarians have a remarkable ability to
completely regenerate a functional nervous system from a pluripotent stem cell population. …
completely regenerate a functional nervous system from a pluripotent stem cell population. …