The origin of new morphological characters is a long-standing problem in evolutionary
biology. Novelties arise through changes in development, but the nature of these changes is …

Whole‐mount in situ hybridization (WISH) is a powerful tool for visualizing gene expression
patterns in specific cell and tissue types. Each model organism presents its own unique set …

… (BJ Pearson, unpublished data, [35]). In contrast, GSEA revealed that stem cell progeny were
enriched in pathways associated with development, differentiation, as well as several other …

▪ Abstract The nervous system of higher organisms exhibits extraordinary cellular diversity
owing to complex spatial and temporal patterning mechanisms. The role of spatial patterning …

Individual neural progenitors generate different cell types in a reproducible order in the
retina 1 , 2 , 3 , cerebral cortex 4 , 5 , 6 and probably in the spinal cord 7 . It is unknown how …

The functions of adult stem cells and tumor suppressor genes are known to intersect. However,
when and how tumor suppressors function in the lineages produced by adult stem cells …

Temporal patterning is an important aspect of embryonic development, but the underlying
molecular mechanisms are not well understood. Drosophila neuroblasts are an excellent …

The ability to discriminate between different chemical stimuli is crucial for food detection,
spatial orientation and other adaptive behaviours in animals. In the nematode Caenorhabditis …

We have constructed an automated learning apparatus to control quantum systems. By
directing intense shaped ultrafast laser pulses into a variety of samples and using a …

In contrast to most well-studied model organisms, planarians have a remarkable ability to
completely regenerate a functional nervous system from a pluripotent stem cell population. …