User profiles for B. D. Marsden
 | Brian MarsdenCentre for Medicines Discovery & Wellcome Centre for Human Genetics Verified email at cmd.ox.ac.uk Cited by 12459 |
[HTML][HTML] Antibody status and incidence of SARS-CoV-2 infection in health care workers
…, A Howarth, SB Hatch, BD Marsden… - … England Journal of …, 2021 - Mass Medical Soc
Background The relationship between the presence of antibodies to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and the risk of subsequent reinfection remains …
syndrome coronavirus 2 (SARS-CoV-2) and the risk of subsequent reinfection remains …
[HTML][HTML] Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom
…, I Diamond, E Rourke, A Howarth, BD Marsden… - Nature …, 2021 - nature.com
We report that in a cohort of 45,965 adults, who were receiving either the ChAdOx1 or the
BNT162b2 SARS-CoV-2 vaccines, in those who had no prior infection with SARS-CoV-2, …
BNT162b2 SARS-CoV-2 vaccines, in those who had no prior infection with SARS-CoV-2, …
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination
…, H Berglund, R Hui, BD Marsden… - Proceedings of the …, 2006 - National Acad Sciences
The 3D structures of human therapeutic targets are enabling for drug discovery. However,
their purification and crystallization remain rate determining. In individual cases, ligands have …
their purification and crystallization remain rate determining. In individual cases, ligands have …
[HTML][HTML] The humoral immune response to HCV: understanding is key to vaccine development
SB Cashman, BD Marsden, LB Dustin - Frontiers in immunology, 2014 - frontiersin.org
Hepatitis C virus (HCV) remains a global problem, despite advances in treatment. The low
cost and high benefit of vaccines have made them the backbone of modern public health …
cost and high benefit of vaccines have made them the backbone of modern public health …
[HTML][HTML] Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison
…, SF Lumley, S Marinou, BD Marsden… - The Lancet Infectious …, 2020 - thelancet.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
global pandemic in 2020. Testing is crucial for mitigating public health and economic effects. …
global pandemic in 2020. Testing is crucial for mitigating public health and economic effects. …
Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study
…, N Jones, L Martins Ferreira, T Christott, BD Marsden… - elife, 2020 - elifesciences.org
We conducted voluntary Covid-19 testing programmes for symptomatic and asymptomatic
staff at a UK teaching hospital using naso-/oro-pharyngeal PCR testing and immunoassays for …
staff at a UK teaching hospital using naso-/oro-pharyngeal PCR testing and immunoassays for …
[HTML][HTML] High-throughput production of human proteins for crystallization: the SGC experience
P Savitsky, J Bray, CDO Cooper, BD Marsden… - Journal of structural …, 2010 - Elsevier
Producing purified human proteins with high yield and purity remains a considerable
challenge. We describe the methods utilized in the Structural Genomics Consortium (SGC) in …
challenge. We describe the methods utilized in the Structural Genomics Consortium (SGC) in …
[HTML][HTML] Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines
Antibody responses are an important part of immunity after Coronavirus Disease 2019 (COVID-19)
vaccination. However, antibody trajectories and the associated duration of protection …
vaccination. However, antibody trajectories and the associated duration of protection …
The duration, dynamics, and determinants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody responses in individual healthcare workers
…, A Howarth, SB Hatch, BD Marsden… - Clinical Infectious …, 2021 - academic.oup.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin
G (IgG) antibody measurements can be used to estimate the proportion of a population …
G (IgG) antibody measurements can be used to estimate the proportion of a population …
[HTML][HTML] Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases
…, C Thangaratnarajah, V Hojzan, BD Marsden… - Journal of Biological …, 2013 - ASBMB
Cullin-RING ligases are multisubunit E3 ubiquitin ligases that recruit substrate-specific
adaptors to catalyze protein ubiquitylation. Cul3-based Cullin-RING ligases are uniquely …
adaptors to catalyze protein ubiquitylation. Cul3-based Cullin-RING ligases are uniquely …