G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions

C Esnault, T Magat, A Zine El Aabidine… - Nature …, 2023 - nature.com
Metazoan promoters are enriched in secondary DNA structure-forming motifs, such as G-quadruplexes
(G4s). Here we describe ‘G4access’, an approach to isolate and sequence G4s …

[HTML][HTML] The control of transcriptional memory by stable mitotic bookmarking

…, H Lenden-Hasse, A Trullo, A Zine El Aabidine… - Nature …, 2022 - nature.com
To maintain cellular identities during development, gene expression profiles must be faithfully
propagated through cell generations. The reestablishment of gene expression patterns …

[HTML][HTML] The known and potential intersections of Rab-GTPases in human papillomavirus infections

JM Young, A Zine El Abidine… - Frontiers in Cell and …, 2019 - frontiersin.org
Papillomaviruses (PVs) were the first viruses recognized to cause tumors and cancers in
mammalian hosts by Shope, nearly a century ago ( Shope and Hurst, 1933 ). Over 40 years ago…

Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers

…, MA Maqbool, A Zine El Aabidine… - Nucleic acids …, 2021 - academic.oup.com
The ubiquitous family of dimeric transcription factors AP-1 is made up of Fos and Jun family
proteins. It has long been thought to operate principally at gene promoters and how it …

Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation

…, V Adoue, A Zine El Aabidine… - Proceedings of the …, 2019 - National Acad Sciences
Naive CD4 + T lymphocytes differentiate into different effector types, including helper and
regulatory cells (Th and Treg, respectively). Heritable gene expression programs that define …

[HTML][HTML] Effects of Ectomycorrhizal Fungi and Heavy Metals (Pb, Zn, and Cd) on Growth and Mineral Nutrition of Pinus halepensis Seedlings in North Africa

…, C Cameselle, S Gouveia, A Zine El Abidine… - Microorganisms, 2020 - mdpi.com
The pollution of soils by heavy metals resulting from mining activities is one of the major
environmental problems in North Africa. Mycorrhizoremediation using mycorrhizal fungi and …

Stomatal and mesophyll limitations of photosynthesis in black spruce seedlings during multiple cycles of drought

JD Stewart, AZ El Abidine, PY Bernier - Tree Physiology, 1995 - academic.oup.com
Container-grown black spruce (Picea mariana (Mill.) BSP) seedlings were planted in trays
containing a sand and peat mixture, and placed in a climate-controlled greenhouse. One …

[PDF][PDF] The landscape of L1 retrotransposons in the human genome is shaped by pre-insertion sequence biases and post-insertion selection

…, O Siol, M Bailly-Bechet, C Philippe, AZ El Aabidine… - Molecular cell, 2019 - cell.com
L1 retrotransposons are transposable elements and major contributors of genetic variation
in humans. Where L1 integrates into the genome can directly impact human evolution and …

De novo assembly of viral quasispecies using overlap graphs

JA Baaijens, AZ El Aabidine, E Rivals… - Genome …, 2017 - genome.cshlp.org
A viral quasispecies, the ensemble of viral strains populating an infected person, can be
highly diverse. For optimal assessment of virulence, pathogenesis, and therapy selection, …

[PDF][PDF] Tyrosine-1 of RNA polymerase II CTD controls global termination of gene transcription in mammals

N Shah, MA Maqbool, Y Yahia, AZ El Aabidine… - Molecular cell, 2018 - cell.com
The carboxy-terminal domain (CTD) of RNA polymerase (Pol) II is composed of a repetition
of YSPTSPS heptads and functions as a loading platform for protein complexes that regulate …