Alignment-free sequence analyses have been applied to problems ranging from whole-genome
phylogeny to the classification of protein families, identification of horizontally …

MicroRNAs (miRNAs) are small non-coding endogenous RNA molecules, 18–24 nucleotides
long, that control multiple gene regulatory pathways via post-transcriptional gene silencing …

Background Alignment-free (AF) sequence comparison is attracting persistent interest driven
by data-intensive applications. Hence, many AF procedures have been proposed in recent …

Background MicroRNAs are the key post-transcriptional regulators of gene expression in
development and stress responses. Thus, precisely quantifying the level of each particular …

Culture-independent approaches have recently shed light on the genomic diversity of viruses
of prokaryotes. One fundamental question when trying to understand their ecological roles …

Phage–Host Interaction Search Tool (PHIST) predicts prokaryotic hosts of viruses based on
exact matches between viral and host genomes. It improves host prediction accuracy at …

In wheat, adult plant resistance (APR) to leaf rust (Puccinia triticina), is effective in restricting
pathogen growth and provides durable resistance against a wide range of virulent forms of P…

Ribosomal 5S RNA (5S rRNA) is the ubiquitous RNA component found in the large subunit
of ribosomes in all known organisms. Due to its small size, abundance and evolutionary …

Abstract Domains in Arabidopsis proteins NRPE1 and SPT5-like, composed almost
exclusively of repeated motifs in which only WG or GW sequences and an overall amino-acid …

Background Characterizing phage–host interactions is critical to understanding the
ecological role of both partners and effective isolation of phage therapeuticals. Unfortunately, …