Ovarian surface epithelium: biology, endocrinology, and pathology
The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer,
arise in the ovarian surface epithelium (OSE). The etiology and early events in the …
arise in the ovarian surface epithelium (OSE). The etiology and early events in the …
[HTML][HTML] The blood-brain barrier: an engineering perspective
It has been more than 100 years since Paul Ehrlich reported that various water-soluble dyes
injected into the circulation did not enter the brain. Since Ehrlich's first experiments, only a …
injected into the circulation did not enter the brain. Since Ehrlich's first experiments, only a …
[HTML][HTML] In Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right Platform
In vitro tumor models have provided important tools for cancer research and serve as low-cost
screening platforms for drug therapies; however, cancer recurrence remains largely …
screening platforms for drug therapies; however, cancer recurrence remains largely …
Classification of 12-lead ecgs: the physionet/computing in cardiology challenge 2020
Objective: Vast 12-lead ECGs repositories provide opportunities to develop new machine
learning approaches for creating accurate and automatic diagnostic systems for cardiac …
learning approaches for creating accurate and automatic diagnostic systems for cardiac …
[HTML][HTML] Factors associated with COVID-19-related death using OpenSAFELY
…, IJ Douglas, CT Rentsch, R Mathur, AYS Wong… - Nature, 2020 - nature.com
Coronavirus disease 2019 (COVID-19) has rapidly affected mortality worldwide 1 . There is
unprecedented urgency to understand who is most at risk of severe outcomes, and this …
unprecedented urgency to understand who is most at risk of severe outcomes, and this …
[HTML][HTML] Massively parallel digital transcriptional profiling of single cells
…, PW Wyatt, CM Hindson, R Bharadwaj, A Wong… - Nature …, 2017 - nature.com
Characterizing the transcriptome of individual cells is fundamental to understanding complex
biological systems. We describe a droplet-based system that enables 3′ mRNA counting …
biological systems. We describe a droplet-based system that enables 3′ mRNA counting …
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
…, B Hedblad, P Nilsson, G Davey Smith, A Wong… - Nature, 2011 - nature.com
Blood pressure is a heritable trait 1 influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm …
to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm …
The MicroArray Quality Control (MAQC) project shows inter-and intraplatform reproducibility of gene expression measurements.
…, SJ Wang, Y Wang, R Wolfinger, A Wong… - Nature …, 2006 - europepmc.org
Over the last decade, the introduction of microarray technology has had a profound impact
on gene expression research. The publication of studies with dissimilar or altogether …
on gene expression research. The publication of studies with dissimilar or altogether …
[HTML][HTML] Pathogenesis and transmission of SARS-CoV-2 in golden hamsters
…, LM Yan, AWH Chin, K Fung, KT Choy, AYL Wong… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus with
high nucleotide identity to SARS-CoV and to SARS-related coronaviruses that have been …
high nucleotide identity to SARS-CoV and to SARS-related coronaviruses that have been …
Fatigue in multiple sclerosis: association with disease-related, behavioural and psychosocial factors
…, S Narayanan, K Arcelin, AN Wong… - Multiple Sclerosis …, 2007 - journals.sagepub.com
We determined biopsychosocial correlates of general, physical, and mental fatigue in MS
patients, by evaluating the additional contribution of potentially modifiable factors after …
patients, by evaluating the additional contribution of potentially modifiable factors after …