Galectins are proteins that regulate immune responses through the recognition of cell-surface
glycans. We present evidence that 16 human galectin genes are expressed at the maternal…

Aryl- (SULT1A1), estrogen- (SULT1E1), and hydroxysteroid- (SULT2A1) sulfotransferases (SULTs)
are active determinants of xenobiotic detoxication and hormone metabolism in the …

INTRODUCTION The microbiota promotes the maturation and homeostasis of the immune
system, in part through the release of microbial products. Early-life microbial colonization has …

Galectin-1 is an anti-inflammatory lectin with pleiotropic regulatory functions at the
crossroads of innate and adaptive immunity. It is expressed in immune privileged sites and is …

Introduction The placenta is arguably the most anatomically variable organ in mammals
even though its primary function is conserved. Method Using RNA-Seq, we measured the …

The host must develop tolerance to commensal microbes and protective responses to
infectious pathogens, yet the mechanisms enabling a privileged relationship with commensals …

In comparison with other primate species, humans have an extended juvenile period during
which the brain is more plastic. In the current study we sought to examine gene expression …

Early-life establishment of tolerance to commensal bacteria at barrier surfaces carries
enduring implications for immune health but remains poorly understood. Here, we showed that …

In anthropoid primates, growth hormone (GH) genes have undergone at least 2 independent
locus expansions, one in platyrrhines (New World monkeys) and another in catarrhines (…

The phylogenetic position of tarsiers within the primates has been a controversial subject for
over a century. Despite numerous morphological and molecular studies, there has been …