User profiles for A. Wargelius

Anna Wargelius

Institute of Marine Reserach
Verified email at imr.no
Cited by 3724

[HTML][HTML] Potential of genome editing to improve aquaculture breeding and production

RL Gratacap, A Wargelius, RB Edvardsen… - Trends in Genetics, 2019 - cell.com
Aquaculture is the fastest growing food production sector and is rapidly becoming the primary
source of seafood for human diets. Selective breeding programs are enabling genetic …

Vertebral deformities in farmed Atlantic salmon (Salmo salar L.) – etiology and pathology

…, EJ Lock, R Waagbø, A Wargelius… - Journal of Applied …, 2012 - Wiley Online Library
The present review sums up and discusses the current literature on occurrence, causation
and pathology of vertebral deformities in farmed Atlantic salmon, and also gives a brief …

Genome editing on finfish: current status and implications for sustainability

TB Blix, RA Dalmo, A Wargelius… - Reviews in …, 2021 - Wiley Online Library
Novel genome editing techniques allow for efficient and targeted improvement of aquaculture
stock and might be a solution to solve challenges related to disease and environmental …

Double–stranded RNA induces specific developmental defects in Zebrafish embryos

A Wargelius, S Ellingsen, A Fjose - Biochemical and biophysical research …, 1999 - Elsevier
Treatment with double-stranded RNA (dsRNA) has been shown to interfere with the function
of specific genes in various invertebrate species. However, it has not yet been reported that …

[HTML][HTML] The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon (Salmo salar L.) Males

…, CJ Rubin, RB Edvardsen, A Wargelius - PLoS …, 2015 - journals.plos.org
Wild and domesticated Atlantic salmon males display large variation for sea age at sexual
maturation, which varies between 1–5 years. Previous studies have uncovered a genetic …

[HTML][HTML] Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon

A Wargelius, S Leininger, KO Skaftnesmo, L Kleppe… - Scientific reports, 2016 - nature.com
Introgression of farmed salmon escapees into wild stocks is a major threat to the genetic
integrity of wild populations. Using germ cell-free fish in aquaculture may mitigate this problem. …

[HTML][HTML] Targeted Mutagenesis in Atlantic Salmon (Salmo salar L.) Using the CRISPR/Cas9 System Induces Complete Knockout Individuals in the F0 Generation

…, S Leininger, L Kleppe, KO Skaftnesmo, A Wargelius - PloS one, 2014 - journals.plos.org
Understanding the biological function behind key proteins is of great concern in Atlantic
salmon, both due to a high commercial importance and an interesting life history. Until recently, …

[HTML][HTML] Functional Annotation of All Salmonid Genomes (FAASG): an international initiative supporting future salmonid research, conservation and aquaculture

…, PM Schulte, A Tello, R Vidal, JO Vik, A Wargelius… - BMC genomics, 2017 - Springer
We describe an emerging initiative - the ‘Functional Annotation of All Salmonid Genomes’ (FAASG),
which will leverage the extensive trait diversity that has evolved since a whole …

Heat shock during early somitogenesis induces caudal vertebral column defects in Atlantic salmon (Salmo salar)

A Wargelius, PG Fjelldal, T Hansen - Development genes and evolution, 2005 - Springer
In several terrestrial vertebrates, heat shock (HS) during somitogenesis causes vertebral
deformities. To determine if vertebral deformities can occur due to sudden temperature changes …

[HTML][HTML] CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and …

…, JO Vik, RB Edvardsen, F Grammes, A Wargelius… - Scientific reports, 2019 - nature.com
Atlantic salmon can synthesize polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic
acid (20:5n-3), arachidonic acid (20:4n-6) and docosahexaenoic acid (22:6n-3) via …