Multiple sclerosis (MS) is a chronic disease with an inflammatory and neurodegenerative
pathology. Axonal loss and neurodegeneration occurs early in the disease course and may …

The face of evolutionary biology is changing: from reconstructing and analysing the past to
predicting future evolutionary processes. Recent developments include prediction of …

T and B cell repertoires are collections of lymphocytes, each characterized by its antigen-specific
receptor. We review here classical technologies and analysis strategies developed to …

Flocking is a typical example of emergent collective behavior, where interactions between
individuals produce collective patterns on the large scale. Here we show how a quantitative …

The anterior insula has been hypothesized to provide a link between attention‐related problem
solving and salience systems during the coordination and evaluation of task performance…

Cancer immunoediting 1 is a hallmark of cancer 2 that predicts that lymphocytes kill more
immunogenic cancer cells to cause less immunogenic clones to dominate a population. …

Temporal lobe epilepsy (TLE) is a devastating disease in which aberrant synaptic plasticity
plays a major role. We identify matrix metalloproteinase (MMP) 9 as a novel synaptic enzyme …

Recognition of pathogens relies on families of proteins showing great diversity. Here we
construct maximum entropy models of the sequence repertoire, building on recent experiments …

An exact steady-state solution of the stochastic equations governing the behavior of a gene
regulated by a self-generated proteomic atmosphere is presented. The solutions depend on …

Stochastic rearrangement of germline V-, D-, and J-genes to create variable coding sequence
for certain cell surface receptors is at the origin of immune system diversity. This process, …