Zebrafish have become a popular organism for the study of vertebrate gene function 1 , 2 .
The virtually transparent embryos of this species, and the ability to accelerate genetic studies …

High-quality and complete reference genome assemblies are fundamental for the application
of genomics to biology, disease, and biodiversity conservation. However, such assemblies …

Genome sequence assemblies provide the basis for our understanding of biology.
Generating error-free assemblies is therefore the ultimate, but sadly still unachieved goal of a …

Tapeworms (Cestoda) cause neglected diseases that can be fatal and are difficult to treat,
owing to inefficient drugs. Here we present an analysis of tapeworm genome sequences using …

Chromosome 6 is a metacentric chromosome that constitutes about 6% of the human
genome. The finished sequence comprises 166,880,988 base pairs, representing the largest …

The reference sequence for each human chromosome provides the framework for understanding
genome function, variation and evolution. Here we report the finished sequence and …

Background: An estimated 1.2 million persons in the United States were living with human
immunodeficiency virus (HIV) infection in 2008. Improving survival of persons with HIV and …

The current human reference genome, GRCh38, represents over 20 years of effort to generate
a high-quality assembly, which has benefitted society 1 , 2 . However, it still has many …

Objective: To determine whether rheumatoid factor (RF), anti-cyclic citrullinated peptide (CCP)
antibodies, or carriage of shared epitope (SE) and PTPN22 genetic susceptibility variants …

In the construction of most projects, a significant role is played by specialty contractors, also
commonly referred to as subcontractors. Despite the importance of subcontractors, little is …