Subjective wellbeing and health are closely linked to age. Three aspects of subjective
wellbeing can be distinguished—evaluative wellbeing (or life satisfaction), hedonic wellbeing (…

The physiological reaction to psychological stress, involving the hypothalamic–pituitary–adrenocortical
and sympatho–adrenomedullary axes, is well characterized, but its link to …

A substantial body of research has investigated the associations between stress-related
psychosocial factors and cancer outcomes. Previous narrative reviews have been inconclusive. …

Both social isolation and loneliness are associated with increased mortality, but it is uncertain
whether their effects are independent or whether loneliness represents the emotional …

Cytoplasmic accumulation and nuclear clearance of TDP-43 characterize familial and sporadic
forms of amyotrophic lateral sclerosis and frontotemporal lobar degeneration, suggesting …

Background: Gender differences in health behaviors have been reported in many studies
but causal mechanisms have been neglected.Purpose and Methods: This study examines 4 …

Objective: A number of mechanisms have been proposed through which social isolation
and loneliness may affect health, including health-related behavioral and biological factors. …

We developed a massive-scale RNA sequencing protocol, short quantitative random RNA
libraries or SQRL, to survey the complexity, dynamics and sequence content of transcriptomes …

The English Longitudinal Study of Ageing (ELSA) is a panel study of a representative cohort
of men and women living in England aged ≥50 years. It was designed as a sister study to …

Introduction Epidemiological studies have shown that weaker grip strength in later life is
associated with disability, morbidity, and mortality. Grip strength is a key component of the …