User profiles for A. Sabantsev
Anton SabantsevPostdoctoral Researcher, Deindl Lab, Uppsala University Verified email at icm.uu.se Cited by 525 |
[HTML][HTML] Recent advances in single-molecule fluorescence microscopy render structural biology dynamic
Highlights • Single-molecule fluorescence microscopy is a powerful tool to study the structural
dynamics of biological macromolecules. • Recent developments in multi-coordinate single-…
dynamics of biological macromolecules. • Recent developments in multi-coordinate single-…
[HTML][HTML] Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling
A Sabantsev, RF Levendosky, X Zhuang… - Nature …, 2019 - nature.com
ATP-dependent chromatin remodelling enzymes (remodellers) regulate DNA accessibility in
eukaryotic genomes. Many remodellers reposition (slide) nucleosomes, however, how DNA …
eukaryotic genomes. Many remodellers reposition (slide) nucleosomes, however, how DNA …
The Chd1 chromatin remodeler shifts hexasomes unidirectionally
RF Levendosky, A Sabantsev, S Deindl, GD Bowman - Elife, 2016 - elifesciences.org
10.7554/eLife.21356.001 Despite their canonical two-fold symmetry, nucleosomes in biological
contexts are often asymmetric: functionalized with post-translational modifications (PTMs)…
contexts are often asymmetric: functionalized with post-translational modifications (PTMs)…
DNA surface exploration and operator bypassing during target search
Many proteins that bind specific DNA sequences search the genome by combining three-dimensional
diffusion with one-dimensional sliding on nonspecific DNA 1 , 2 , 3 , 4 – 5 . Here …
diffusion with one-dimensional sliding on nonspecific DNA 1 , 2 , 3 , 4 – 5 . Here …
Extracellular membrane vesicles secreted by mycoplasma Acholeplasma laidlawii PG8 are enriched in virulence proteins
Mycoplasmas (class Mollicutes), the smallest prokaryotes capable of self-replication, as well
as Archaea, Gram-positive and Gram-negative bacteria constitutively produce extracellular …
as Archaea, Gram-positive and Gram-negative bacteria constitutively produce extracellular …
[PDF][PDF] Mechanistic insights into regulation of the ALC1 remodeler by the nucleosome acidic patch
Upon DNA damage, the ALC1/CHD1L nucleosome remodeling enzyme (remodeler) is
activated by binding to poly(ADP-ribose). How activated ALC1 recognizes the nucleosome, as …
activated by binding to poly(ADP-ribose). How activated ALC1 recognizes the nucleosome, as …
[HTML][HTML] Spatiotemporally controlled generation of NTPs for single-molecule studies
Many essential processes in the cell depend on proteins that use nucleoside triphosphates (NTPs).
Methods that directly monitor the often-complex dynamics of these proteins at the …
Methods that directly monitor the often-complex dynamics of these proteins at the …
Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome
The chromatin remodeler ALC1 is recruited to and activated by DNA damage-induced poly (ADP-ribose)(PAR)
chains deposited by PARP1/PARP2/HPF1 upon detection of DNA lesions…
chains deposited by PARP1/PARP2/HPF1 upon detection of DNA lesions…
[HTML][HTML] Detection of spacer precursors formed in vivo during primed CRISPR adaptation
…, N Morozova, A Metlitskaya, A Sabantsev… - Nature …, 2019 - nature.com
Type I CRISPR-Cas loci provide prokaryotes with a nucleic-acid-based adaptive immunity
against foreign DNA. Immunity involves adaptation, the integration of ~30-bp DNA fragments, …
against foreign DNA. Immunity involves adaptation, the integration of ~30-bp DNA fragments, …
Temporal dynamics of methyltransferase and restriction endonuclease accumulation in individual cells after introducing a restriction-modification system
N Morozova, A Sabantsev, E Bogdanova… - Nucleic acids …, 2016 - academic.oup.com
Type II restriction-modification (RM) systems encode a restriction endonuclease that cleaves
DNA at specific sites, and a methyltransferase that modifies same sites protecting them from …
DNA at specific sites, and a methyltransferase that modifies same sites protecting them from …