Precursor mRNA splicing is one of the most highly regulated processes in metazoan species.
In addition to generating vast repertoires of RNAs and proteins, splicing has a profound …

Recursive splicing is a process in which large introns are removed in multiple steps by re-splicing
at ratchet points—5′ splice sites recreated after splicing 1 . Recursive splicing was …

While much attention has been focused on chromatin at promoters and exons, human genes
are mostly composed of intronic sequences. Analyzing published surveys of nucleosomes …

Three-fourths of the recognition-dependent disease resistance genes (R-genes) identified
in plants encode nucleotide binding site (NBS) leucine-rich repeat (LRR) proteins. NBS-LRR …

Effectively monitoring the spread of SARS-CoV-2 mutants is essential to efforts to counter the
ongoing pandemic. Predicting lineage abundance from wastewater, however, is technically …

Background Duplications of the chromosome 15q11-q13.1 region are associated with an
estimated 1 to 3% of all autism cases, making this copy number variation (CNV) one of the …

Intracellular trafficking of the glucose transporter GLUT4 from storage compartments to the
plasma membrane is triggered in muscle and fat during the body’s response to insulin. …

Effectively monitoring the spread of SARS-CoV-2 variants is essential to efforts to counter
the ongoing pandemic. Wastewater monitoring of SARS-CoV-2 RNA has proven an effective …

Background Variation in the COMT gene has been implicated in a number of psychiatric
disorders, including psychotic, affective and anxiety disorders. The majority of these studies …

Linkage and association studies have recently implicated dystrobrevin-binding protein 1 (DTNBP1)
in the etiology of schizophrenia. We analyzed seven previously tested DTNBP1 …