User profiles for A. Pelling

Andrew E. Pelling

Pelling Lab for Augmented Biology
Verified email at pellinglab.net
Cited by 5113

Investigating cell mechanics with atomic force microscopy

K Haase, AE Pelling - Journal of The Royal Society …, 2015 - royalsocietypublishing.org
Transmission of mechanical force is crucial for normal cell development and functioning.
However, the process of mechanotransduction cannot be studied in isolation from cell …

[HTML][HTML] Cellulose biomaterials for tissue engineering

RJ Hickey, AE Pelling - Frontiers in bioengineering and …, 2019 - frontiersin.org
In this review, we highlight the importance of nanostructure of cellulose-based biomaterials
to allow cellular adhesion, the contribution of nanostructure to macroscale mechanical …

Force nanoscopy of cell mechanics and cell adhesion

YF Dufrêne, AE Pelling - Nanoscale, 2013 - pubs.rsc.org
Cells are constantly exposed to mechanical stimuli in their environment and have several
evolved mechanisms to sense and respond to these cues. It is becoming increasingly …

Sox2 is required for sensory organ development in the mammalian inner ear

AE Kiernan, AL Pelling, KKH Leung, ASP Tang… - Nature, 2005 - nature.com
Sensory hair cells and their associated non-sensory supporting cells in the inner ear are
fundamental for hearing and balance. They arise from a common progenitor 1 , but little is …

Local Nanomechanical Motion of the Cell Wall of Saccharomyces cerevisiae

AE Pelling, S Sehati, EB Gralla, JS Valentine… - Science, 2004 - science.org
We demonstrate that the cell wall of living Saccharomyces cerevisiae (baker's yeast) exhibits
local temperature-dependent nanomechanical motion at characteristic frequencies. The …

[HTML][HTML] Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis

P Kunda, AE Pelling, T Liu, B Baum - Current biology, 2008 - cell.com
Background During mitosis, animal cells undergo a complex sequence of morphological
changes, from retraction of the cell margin and cell rounding at the onset of mitosis to axial …

Characterization of the interface between normal and transformed epithelial cells

…, M Norman, M Kajita, C Zimmermann, AE Pelling… - Nature cell …, 2009 - nature.com
In most cancers, transformation begins in a single cell in an epithelial cell sheet 1 , 2 , 3 .
However, it is not known what happens at the interface between non-transformed (normal) and …

[HTML][HTML] Biocompatibility of subcutaneously implanted plant-derived cellulose biomaterials

DJ Modulevsky, CM Cuerrier, AE Pelling - PloS one, 2016 - journals.plos.org
There is intense interest in developing novel biomaterials which support the invasion and
proliferation of living cells for potential applications in tissue engineering and regenerative …

[HTML][HTML] Apple derived cellulose scaffolds for 3D mammalian cell culture

…, C Lefebvre, K Haase, Z Al-Rekabi, AE Pelling - PloS one, 2014 - journals.plos.org
There are numerous approaches for producing natural and synthetic 3D scaffolds that
support the proliferation of mammalian cells. 3D scaffolds better represent the natural cellular …

Nanoscale visualization and characterization of Myxococcus xanthus cells with atomic force microscopy

AE Pelling, Y Li, W Shi… - Proceedings of the …, 2005 - National Acad Sciences
Multicellular microbial communities are the predominant form of existence for microorganisms
in nature. As one of the most primitive social organisms, Myxococcus xanthus has been an …