Solubilization and refolding of bacterial inclusion body proteins
SM Singh, AK Panda - Journal of bioscience and bioengineering, 2005 - Elsevier
Inclusion bodies produced in Escherichia coli are composed of densely packed denatured
protein molecules in the form of particles. Refolding of inclusion body proteins into bioactive …
protein molecules in the form of particles. Refolding of inclusion body proteins into bioactive …
Aging of the innate immune system
AC Shaw, S Joshi, H Greenwood, A Panda… - Current opinion in …, 2010 - Elsevier
The innate immune system is composed of a network of cells including neutrophils, NK and
NKT cells, monocytes/macrophages, and dendritic cells that mediate the earliest interactions …
NKT cells, monocytes/macrophages, and dendritic cells that mediate the earliest interactions …
Circular RNAs act as miRNA sponges
AC Panda - Circular RNAs: biogenesis and functions, 2018 - Springer
Majority of RNAs expressed in animal cells lack protein-coding ability. Unlike other cellular
RNAs, circular (circ)RNAs include a large family of noncoding (nc)RNAs that lack the 5′ or 3…
RNAs, circular (circ)RNAs include a large family of noncoding (nc)RNAs that lack the 5′ or 3…
MitoCarta3. 0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
The mammalian mitochondrial proteome is under dual genomic control, with 99% of
proteins encoded by the nuclear genome and 13 originating from the mitochondrial DNA (mtDNA). …
proteins encoded by the nuclear genome and 13 originating from the mitochondrial DNA (mtDNA). …
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
…, DE Comstock, SA Weiss, FD Brown, A Panda… - Nature …, 2019 - nature.com
T cell dysfunction is a hallmark of many cancers, but the basis for T cell dysfunction and the
mechanisms by which antibody blockade of the inhibitory receptor PD-1 (anti-PD-1) …
mechanisms by which antibody blockade of the inhibitory receptor PD-1 (anti-PD-1) …
BlinkDB: queries with bounded errors and bounded response times on very large data
In this paper, we present BlinkDB, a massively parallel, approximate query engine for running
interactive SQL queries on large volumes of data. BlinkDB allows users to trade-off query …
interactive SQL queries on large volumes of data. BlinkDB allows users to trade-off query …
Human innate immunosenescence: causes and consequences for immunity in old age
The past decade has seen an explosion in research focusing on innate immunity. Through
a wide range of mechanisms including phagocytosis, intracellular killing and activation of …
a wide range of mechanisms including phagocytosis, intracellular killing and activation of …
Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1
HuR influences gene expression programs and hence cellular phenotypes by binding to
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular RNAs …
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular RNAs …
[HTML][HTML] Protein recovery from inclusion bodies of Escherichia coli using mild solubilization process
Formation of inclusion bodies in bacterial hosts poses a major challenge for large scale
recovery of bioactive proteins. The process of obtaining bioactive protein from inclusion bodies …
recovery of bioactive proteins. The process of obtaining bioactive protein from inclusion bodies …
Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response
We evaluated TLR function in primary human dendritic cells (DCs) from 104 young (age 21–30
y) and older (≥ 65 y) individuals. We used multicolor flow cytometry and intracellular …
y) and older (≥ 65 y) individuals. We used multicolor flow cytometry and intracellular …