[HTML][HTML] Widespread shortening of 3'untranslated regions and increased exon inclusion are evolutionarily conserved features of innate immune responses to infection

AA Pai, G Baharian, A Pagé Sabourin… - PLoS …, 2016 - journals.plos.org
The contribution of pre-mRNA processing mechanisms to the regulation of immune responses
remains poorly studied despite emerging examples of their role as regulators of immune …

[PDF][PDF] Genetic ancestry and natural selection drive population differences in immune responses to pathogens

…, A Freiman, AJ Sams, S Hebert, AP Sabourin… - Cell, 2016 - cell.com
Individuals from different populations vary considerably in their susceptibility to immune-related
diseases. To understand how genetic variation and natural selection contribute to these …

Dynamic selection of classifiers—a comprehensive review

AS Britto Jr, R Sabourin, LES Oliveira - Pattern recognition, 2014 - Elsevier
… An interesting approach was proposed in 1993 by Sabourin et al. in [12], referred in this
paper as the DSC-Rank (see Algorithm 1). It may be considered as one of the pioneers in DS. In …

Ste20-like kinase SLK, at the crossroads: a matter of life and death

KN Al-Zahrani, KD Baron, LA Sabourin - Cell adhesion & migration, 2013 - Taylor & Francis
… SLK was first characterized by Sabourin and Rudnicki in 1999 as a mediator of apoptosis.
Stable overexpression of SLK in C2C12 myoblasts induced apoptosis via a c-Jun N-terminal …

Self/non‐self discrimination by human γδ T cells: simple solutions for a complex issue?

A Thedrez, C Sabourin, J Gertner… - Immunological …, 2007 - Wiley Online Library
Although γδ T cells express clonally distributed T‐cell receptors (TCRs), a hallmark of
adaptive immunity, they are classically considered as innate‐like effectors, owing to the high …

Nontargeted analysis study reporting tool: a framework to improve research transparency and reproducibility

…, KE Miller, M Pristner, L Sabourin… - Analytical …, 2021 - ACS Publications
Non-targeted analysis (NTA) workflows using mass spectrometry are gaining popularity in
many disciplines, but universally accepted reporting standards are nonexistent. Current …

[HTML][HTML] PDZK1: I. a major scaffolder in brush borders of proximal tubular cells

…, D Bacic, P Forrer, A Gantenbein, LA Sabourin… - Kidney international, 2003 - Elsevier
… were released with 35 μL elution buffer (50 mmol/L NaH 2 PO 4 , 5 mmol/L Tris-HCl, pH
8.0, 300 mmol/L NaCl, 250 mmol/L imidazole, and 0.005% Tween-20), separated on SDS-PAGE

[PDF][PDF] Integrative analyses of colorectal cancer show immunoscore is a stronger predictor of patient survival than microsatellite instability

…, A Berger, P Bruneval, JJ Tuech, JC Sabourin… - Immunity, 2016 - cell.com
Microsatellite instability in colorectal cancer predicts favorable outcomes. However, the
mechanistic relationship between microsatellite instability, tumor-infiltrating immune cells, …

A flexible protein linker improves the function of epitope‐tagged proteins in Saccharomyces cerevisiae

M Sabourin, CT Tuzon, TS Fisher, VA Zakian - Yeast, 2007 - Wiley Online Library
Epitope tagging permits the detection of proteins when protein‐specific antibodies are not
available. However, the epitope tag can reduce the function of the tagged protein. Here we …

DESlib: A Dynamic ensemble selection library in Python

RMO Cruz, LG Hafemann, R Sabourin… - Journal of Machine …, 2020 - jmlr.org
DESlib is an open-source python library providing the implementation of several dynamic
selection techniques. The library is divided into three modules: (i) dcs, containing the …