Mass spectrometry (MS)-based proteomics has become a powerful technology to quantify
the entire complement of proteins in cells or tissues. Here, we review challenges and recent …

Aging is emerging as a druggable target with growing interest from academia, industry and
investors. New technologies such as artificial intelligence and advanced screening …

Single‐cell technologies are revolutionizing biology but are today mainly limited to imaging
and deep sequencing. However, proteins are the main drivers of cellular function and in‐…

Despite the availabilty of imaging-based and mass-spectrometry-based methods for spatial
proteomics, a key challenge remains connecting images with single-cell-resolution protein …

The posttranslational modification of proteins by arginine methylation is functionally important,
yet the breadth of this modification is not well characterized. Using high-resolution mass …

Single-cell proteomics by mass spectrometry is emerging as a powerful and unbiased method
for the characterization of biological heterogeneity. So far, it has been limited to cultured …

Viral proteins make extensive use of short peptide interaction motifs to hijack cellular host
factors. However, most current large-scale methods do not identify this important class of …

The CHD1 gene, encoding the chromo‐domain helicase DNA‐binding protein‐1, is one of
the most frequently deleted genes in prostate cancer. Here, we examined the role of CHD1 in …

Due to the central role of cranes in construction operations, specialists in the construction
industries have cooperated in the development of structured methods and software for crane …

… Mund is Associate Professor and Division Director, Anesthesia for Nurses, Medical University
of South Carolina, Charleston, South Carolina. The authors thank Dr. Kay Sackett for her …