Genome-wide measurements of protein-DNA interactions and transcriptomes are increasingly
done by deep DNA sequencing methods (ChIP-seq and RNA-seq). The power and …

RNA-sequencing (RNA-seq) has a wide variety of applications, but no single analysis
pipeline can be used in all cases. We review all of the major steps in RNA-seq data analysis, …

Eukaryotic cells make many types of primary and processed RNAs that are found either in
specific subcellular compartments or throughout the cells. A complete catalogue of these …

High-throughput mRNA sequencing (RNA-Seq) promises simultaneous transcript discovery
and abundance estimation 1 , 2 , 3 . However, this would require algorithms that are not …

We have mapped and quantified mouse transcriptomes by deeply sequencing them and
recording how frequently each gene is represented in the sequence sample (RNA-Seq). This …

The human and mouse genomes contain instructions that specify RNAs and proteins and
govern the timing, magnitude, and cellular context of their production. To better delineate these …

Bladder cancer is a significant health burden due to its high prevalence, risk of mortality,
morbidity, and high cost of medical care. Epidemiologic evidence suggests that diets rich in …

In vivo protein-DNA interactions connect each transcription factor with its direct targets to form
a gene network scaffold. To map these protein-DNA interactions comprehensively across …

Energy filtering has been a long-sought strategy to enhance a thermoelectric material's
figure of merit zT through improving its power factor. Here we show a composite of multi-layer …

The NCCN Guidelines for Kidney Cancer focus on the screening, diagnosis, staging, treatment,
and management of renal cell carcinoma (RCC). Patients with relapsed or stage IV RCC …