Mesenchymal stem cells in cartilage repair: state of the art and methods to monitor cell growth, differentiation and cartilage regeneration
…, W Grill, B Fuchs, JA Kas, A Krinner… - Current medicinal …, 2010 - ingentaconnect.com
Degenerative joint diseases caused by rheumatism, joint dysplasia or traumata are
particularly widespread in countries with high life expectation. Although there is no absolutely …
particularly widespread in countries with high life expectation. Although there is no absolutely …
Impact of oxygen environment on mesenchymal stem cell expansion and chondrogenic differentiation
A Krinner, M Zscharnack, A Bader, D Drasdo… - Cell …, 2009 - Wiley Online Library
Introduction: In vitro expansion and differentiation of mesenchymal stem cells (MSC) rely on
specific environmental conditions, and investigations have demonstrated that one crucial …
specific environmental conditions, and investigations have demonstrated that one crucial …
In vivo time-lapse imaging shows diverse niche engagement by quiescent and naturally activated hematopoietic stem cells
…, MK Scott, N Scherf, A Krinner… - Blood, The Journal …, 2014 - ashpublications.org
Hematopoietic stem cells (HSCs) maintain the turnover of mature blood cells during steady
state and in response to systemic perturbations such as infections. Their function critically …
state and in response to systemic perturbations such as infections. Their function critically …
[HTML][HTML] Merging concepts-coupling an agent-based model of hematopoietic stem cells with an ODE model of granulopoiesis
A Krinner, I Roeder, M Loeffler, M Scholz - BMC systems biology, 2013 - Springer
Background Hematopoiesis is a complex process involving different cell types and feedback
mechanisms mediated by cytokines. This complexity stimulated various models with …
mechanisms mediated by cytokines. This complexity stimulated various models with …
[HTML][HTML] Individual fates of mesenchymal stem cells in vitro
Background In vitro cultivated stem cell populations are in general heterogeneous with
respect to their expression of differentiation markers. In hematopoietic progenitor populations, …
respect to their expression of differentiation markers. In hematopoietic progenitor populations, …
[HTML][HTML] Full dynamic ball bearing model with elastic outer ring for high speed applications
C Wagner, A Krinner, T Thümmel, D Rixen - Lubricants, 2017 - mdpi.com
Ball bearings are commonly used in high speed turbomachinery and have a critical influence
on the rotordynamic behavior. Therefore, a simulation model of the bearing to predict the …
on the rotordynamic behavior. Therefore, a simulation model of the bearing to predict the …
Quantification and modeling of stem cell–niche interaction
A Krinner, I Roeder - A Systems Biology Approach to Blood, 2014 - Springer
Adult stem cells persist lifelong in the organism, where they are responsible for tissue homeostasis
and repair. It is commonly assumed that their maintenance and function are facilitated …
and repair. It is commonly assumed that their maintenance and function are facilitated …
Bistable epigenetic states explain age-dependent decline in mesenchymal stem cell heterogeneity
Z Hamidouche, K Rother, J Przybilla, A Krinner… - Stem Cells, 2017 - academic.oup.com
The molecular mechanisms by which heterogeneity, a major characteristic of stem cells, is
achieved are yet unclear. We here study the expression of the membrane stem cell antigen-1 (…
achieved are yet unclear. We here study the expression of the membrane stem cell antigen-1 (…
Single cell phenotyping reveals heterogeneity among hematopoietic stem cells following infection
…, R Khorshed, NM Rashidi, N Scherf, A Krinner… - Stem Cells, 2017 - academic.oup.com
The hematopoietic stem cell (HSC) niche provides essential microenvironmental cues for
the production and maintenance of HSCs within the bone marrow. During inflammation, …
the production and maintenance of HSCs within the bone marrow. During inflammation, …
Plasma‐free vs deconjugated metanephrines for diagnosis of phaeochromocytoma
…, JWM Lenders, K Pacak, A Krinner… - Clinical …, 2013 - Wiley Online Library
Background The diagnosis of phaeochromocytoma is commonly performed by the
measurements of plasma‐free normetanephrine and metanephrine. Plasma‐deconjugated …
measurements of plasma‐free normetanephrine and metanephrine. Plasma‐deconjugated …