User profiles for A. Klimas
Aleksandra KlimasCarnegie Mellon University Verified email at andrew.cmu.edu Cited by 888 |
Cardiac applications of optogenetics
In complex multicellular systems, such as the brain or the heart, the ability to selectively
perturb and observe the response of individual components at the cellular level and with …
perturb and observe the response of individual components at the cellular level and with …
The organized nonlinear dynamics of the magnetosphere
AJ Klimas, D Vassiliadis, DN Baker… - Journal of Geophysical …, 1996 - Wiley Online Library
The linear prediction filters computed by Bargatze et al. [1985] have resulted in a turning
point in the study of solar wind‐magnetosphere coupling. The evolution of the filters with …
point in the study of solar wind‐magnetosphere coupling. The evolution of the filters with …
New measure of the dissipation region in collisionless magnetic reconnection
S Zenitani, M Hesse, A Klimas, M Kuznetsova - Physical review letters, 2011 - APS
A new measure to identify a small-scale dissipation region in collisionless magnetic
reconnection is proposed. The energy transfer from the electromagnetic field to plasmas in the …
reconnection is proposed. The energy transfer from the electromagnetic field to plasmas in the …
[HTML][HTML] Multimodal on-axis platform for all-optical electrophysiology with near-infrared probes in human stem-cell-derived cardiomyocytes
A Klimas, G Ortiz, SC Boggess, EW Miller… - Progress in biophysics …, 2020 - Elsevier
Combined optogenetic stimulation and optical imaging permit scalable, contact-free high-throughput
probing of cellular electrophysiology and optimization of stem-cell derived excitable …
probing of cellular electrophysiology and optimization of stem-cell derived excitable …
[HTML][HTML] OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology
The improvement of preclinical cardiotoxicity testing, discovery of new ion-channel-targeted
drugs, and phenotyping and use of stem cell-derived cardiomyocytes and other biologics all …
drugs, and phenotyping and use of stem cell-derived cardiomyocytes and other biologics all …
Optical control of excitation waves in cardiac tissue
In nature, macroscopic excitation waves 1 , 2 are found in a diverse range of settings
including chemical reactions, metal rust, yeast, amoeba and the heart and brain. In the case of …
including chemical reactions, metal rust, yeast, amoeba and the heart and brain. In the case of …
[HTML][HTML] Computational optogenetics: empirically-derived voltage-and light-sensitive channelrhodopsin-2 model
Channelrhodospin-2 (ChR2), a light-sensitive ion channel, and its variants have emerged as
new excitatory optogenetic tools not only in neuroscience, but also in other areas, including …
new excitatory optogenetic tools not only in neuroscience, but also in other areas, including …
Three-dimensional nanofabrication via ultrafast laser patterning and kinetically regulated material assembly
A major challenge in nanotechnology is the fabrication of complex three-dimensional (3D)
structures with desired materials. We present a strategy for fabricating arbitrary 3D …
structures with desired materials. We present a strategy for fabricating arbitrary 3D …
The evolution from weak to strong geomagnetic activity: An interpretation in terms of deterministic chaos
DN Baker, AJ Klimas, RL McPherron… - Geophysical Research …, 1990 - Wiley Online Library
Linear prediction filtering techniques have shown that the magnetospheric response to
energy transfer from the solar wind contains both driven and unloading components. Filter …
energy transfer from the solar wind contains both driven and unloading components. Filter …
Self‐organized criticality in the substorm phenomenon and its relation to localized reconnection in the magnetospheric plasma sheet
AJ Klimas, JA Valdivia, D Vassiliadis… - Journal of …, 2000 - Wiley Online Library
Evidence is presented that suggests that there is a significant self‐organized criticality (SOC)
component in the dynamics of substorms in the magnetosphere. We assume that …
component in the dynamics of substorms in the magnetosphere. We assume that …