Flavonoids are present in almost all terrestrial plants, where they provide UV-protection and
colour. Flavonoids have a fused ring system consisting of an aromatic ring and a …

Many autoimmune diseases are driven by self‐reactive T helper cells. Until recently, organ‐specific
autoimmune diseases were primarily associated with Th1 cells but not Th2 cells. …

The cyclin-dependent kinase (CDK) 4/6 inhibitors belong to a new class of drugs that interrupt
proliferation of malignant cells by inhibiting progression through the cell cycle. Three such …

Acute myeloid leukemia (AML) manifests as phenotypically and functionally diverse cells,
often within the same patient. Intratumor phenotypic and functional heterogeneity have been …

Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for ∼9…

Experimental autoimmune encephalomyelitis (EAE) is a model of human multiple sclerosis
induced by autoreactive Th cells that mediate tissue inflammation and demyelination in the …

Industry is currently undergoing a transformation towards full digitalization and intelligentization
of manufacturing processes. Visionary but quite realistic concepts such as the Internet of …

Background The randomized, double-blind OlympiA trial compared 1 year of the oral poly(adenosine
diphosphate-ribose) polymerase inhibitor, olaparib, to matching placebo as …

Mass cytometry uses atomic mass spectrometry combined with isotopically pure reporter
elements to currently measure as many as 40 parameters per single cell. As with any …

The hydraulic function of three types of macropores during saturated flow through four swelling
fine clayey and very fine clayey soil horizons was characterized with methylene blue as a …