Understanding the ecological consequences of biodiversity is a fundamental challenge.
Research on a key component of biodiversity, genetic diversity, has traditionally focused on its …

Objective To examine the risk of suicidal behaviour within clinical trials of antidepressants in
adults. Design Meta-analysis of 372 double blind randomised placebo controlled trials. …

▪ Abstract The loci of the vertebrate major histocompatibility complex encode cell-surface
glycoproteins that present peptides to T cells. Certain of these loci are highly polymorphic, and …

During development, oligodendrocytes contact and wrap neuronal axons with myelin.
Similarly to neurons and synapses, excess myelin sheaths are produced and selectively …

Coastal ecosystems and the services they provide are adversely affected by a wide variety
of human activities. In particular, seagrass meadows are negatively affected by impacts …

Background— Different blood pressure (BP)–lowering drugs could have different effects on
central aortic pressures and thus cardiovascular outcome despite similar effects on brachial …

Background Hypersensitivity reaction to abacavir is strongly associated with the presence of
the HLA-B*5701 allele. This study was designed to establish the effectiveness of …

The function of a surgical bone screw is to clamp together the bone and a bone plate or to
fix bone fragments. This is achieved by the generation of a tensile stress along the length of …

Background Valproate is widely accepted as a drug of first choice for patients with generalised
onset seizures, and its broad spectrum of efficacy means it is recommended for patients …

Although progesterone has been recognized as essential for the establishment and maintenance
of pregnancy, this steroid hormone has been recently implicated to have a functional …