Understanding the mechanisms of learning requires characterizing how the response properties
of individual neurons and interactions across populations of neurons change over time. …

The rise of big data in modern research poses serious challenges for data management: Large
and intricate datasets from diverse instrumentation must be precisely aligned, annotated, …

The forced swimming test of rats or mice is a frequently used behavioral test to evaluate
compounds for antidepressant activity in vivo. The aim of this study was to replace the human …

Given the large social impact of dietary advice, it is important that the advice have a solid
scientific basis. Evidence-based dietary advice should be built on results from all studies …

Among the many concerns for biodiversity in the Anthropocene, recent reports of flying insect
loss are particularly alarming, given their importance as pollinators, pest control agents, …

This paper reports on a literary corpus study of four grammatical tenses across four
European languages. The corpus consists of a selection of eight chapters from Javier Marías’s …

Lynch syndrome patients are susceptible to colorectal and endometrial cancers owing to
inactivating germline mutations in mismatch repair genes, including MSH2 (ref. 1 ). Here we …

Longitudinal bone growth is the result of endochondral bone formation which takes place in
the growth plate. The rate of chondrocyte proliferation and hypertrophy, vascular invasion …

Recently, we identified 3′ end deletions in the EPCAM gene as a novel cause of Lynch
syndrome. These truncating EPCAM deletions cause allele‐specific epigenetic silencing of the …

In the majority of colorectal cancers (CRCs) under clinical suspicion for a hereditary cause,
the disease‐causing genetic factors are still to be discovered. To identify such genetic factors …