User profiles for A. Greninger

Alex Greninger

University of Washington
Verified email at uw.edu
Cited by 23485

[HTML][HTML] Covid-19 in critically ill patients in the Seattle region—case series

…, KR Jerome, AK Nalla, AL Greninger… - … England Journal of …, 2020 - Mass Medical Soc
Background Community transmission of coronavirus 2019 (Covid-19) was detected in the
state of Washington in February 2020. Methods We identified patients from nine Seattle-area …

The laboratory diagnosis of coronavirus disease 2019—frequently asked questions

…, SN Naccache, AL Greninger - Clinical Infectious …, 2020 - academic.oup.com
Diagnostic testing has played and will continue to play a major role in the coronavirus
disease 2019 (COVID-19) pandemic. The ability to detect severe acute respiratory syndrome …

The challenge of diagnostic metagenomics

AL Greninger - Expert review of molecular diagnostics, 2018 - Taylor & Francis
Introduction: Diagnostic metagenomics and its associated trail of publications are spreading
across the world. Multiple clinical labs in the United States, Europe, and Asia have gone to …

[HTML][HTML] Efficacy and safety of NVX-CoV2373 in adults in the United States and Mexico

…, KM Neuzil, RW Coombs, AL Greninger… - … England Journal of …, 2022 - Mass Medical Soc
Background NVX-CoV2373 is an adjuvanted, recombinant spike protein nanoparticle vaccine
that was shown to have clinical efficacy for the prevention of coronavirus disease 2019 (…

[HTML][HTML] Detection of SARS-CoV-2 with SHERLOCK one-pot testing

…, BD Walker, DT Hung, AL Greninger… - … England Journal of …, 2020 - Mass Medical Soc
Detection of SARS-CoV-2 with a CRISPR-Based Test A new method for the detection of
SARS-CoV-2 combines simplified extraction of RNA with isothermal amplification and CRISPR (…

Comparative performance of SARS-CoV-2 detection assays using seven different primer-probe sets and one assay kit

…, Y Wei, H Zhu, KR Jerome, AL Greninger - Journal of clinical …, 2020 - Am Soc Microbiol
Nearly 400,000 people worldwide are known to have been infected with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) beginning in December 2019. The virus has …

Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with a high attack rate

…, KR Jerome, JD Bloom, AL Greninger - Journal of clinical …, 2020 - Am Soc Microbiol
The development of vaccines against SARS-CoV-2 would be greatly facilitated by the
identification of immunological correlates of protection in humans. However, to date, studies on …

Performance characteristics of the Abbott Architect SARS-CoV-2 IgG assay and seroprevalence in Boise, Idaho

…, KR Jerome, PC Mathias, AL Greninger - Journal of clinical …, 2020 - Am Soc Microbiol
Coronavirus disease 2019 (COVID-19), the novel respiratory illness caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is associated with severe morbidity and …

[PDF][PDF] SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses

…, EA Goecker, EJ Degli-Angeli, J Logue, A Greninger… - Cell, 2022 - cell.com
Although infections among vaccinated individuals lead to milder COVID-19 symptoms
relative to those in unvaccinated subjects, the specificity and durability of antibody responses …

[HTML][HTML] Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis

AL Greninger, SN Naccache, S Federman, G Yu… - Genome medicine, 2015 - Springer
We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV),
and hepatitis C virus (HCV) from four human blood samples by MinION nanopore …