Epithelial cancers make up the vast majority of cancer types and, during the transition from
benign adenoma to malignant carcinoma and metastasis, epithelial tumor cells acquire a de-…

Epithelial–mesenchymal transition (EMT) is a process whereby epithelial cells are transcriptionally
reprogrammed, resulting in decreased adhesion and enhanced migration or invasion…

ZEB1 and ZEB2, which are members of the ZEB family of transcription factors, play a pivotal
role in the development of the vertebrate embryo. However, recent evidence shows that both …

Deregulation of signaling pathways that control differentiation, expansion and migration of
neural crest-derived melanoblasts during normal development contributes also to melanoma …

We completed a multicenter study of the effects of pomegranate cold-pressed (Oil) or
supercritical CO 2 -extracted (S) seed oil, fermented juice polyphenols (W), and pericarp …

Several studies indicate that cancer-associated fibroblasts play a critical role in cancer cell
invasion and metastasis, the hallmarks of malignancy. To better understand the mechanisms …

Introduction P‐glycoprotein (P‐gp) is an efflux transporter responsible for the transport of
various drugs across the blood‐brain barrier (BBB). Loss of P‐gp function with age may be one …

Background Cancer cells are able to change the protein expression and behavior of non-cancerous
surrounding cells. Exosomes, secreted by prostate cancer (PCa) cells, may have a …

In many cancer types, the expression and function of∼ 22 nucleotide-long microRNAs (miRNA)
is deregulated. Mature miRNAs can be stably detected in extracellular vesicles (EVs) in …

Deletions on the long arm of the Y chromosome are a well‐known cause of male infertility
and it is generally accepted that deletions involving the AZF b region are not compatible with …