User profiles for A. Destexhe

Alain Destexhe

CNRS
Verified email at unic.cnrs-gif.fr
Cited by 29331

The high-conductance state of neocortical neurons in vivo

A Destexhe, M Rudolph, D Paré - Nature reviews neuroscience, 2003 - nature.com
Intracellular recordings in vivo have shown that neocortical neurons are subjected to an
intense synaptic bombardment in intact networks and are in a 'high-conductance' state. In vitro …

Why do we sleep?

TJ Sejnowski, A Destexhe - Brain research, 2000 - Elsevier
Slow-wave sleep consists in slowly recurring waves that are associated with a large-scale
spatio-temporal synchrony across neocortex. These slow-wave complexes alternate with brief …

Are corticothalamic 'up'states fragments of wakefulness?

A Destexhe, SW Hughes, M Rudolph, V Crunelli - Trends in neurosciences, 2007 - cell.com
The slow (<1Hz) oscillation, with its alternating ‘up' and ‘down' states in individual neurons,
is a defining feature of the electroencephalogram (EEG) during slow-wave sleep (SWS). …

Low-dimensional chaos in an instance of epilepsy.

A Babloyantz, A Destexhe - Proceedings of the National …, 1986 - National Acad Sciences
Using a time series obtained from the electroencephalogram recording of a human epileptic
seizure, we show the existence of a chaotic attractor, the latter being the direct consequence …

Fluctuating synaptic conductances recreate in vivo-like activity in neocortical neurons

A Destexhe, M Rudolph, JM Fellous, TJ Sejnowski - Neuroscience, 2001 - Elsevier
To investigate the basis of the fluctuating activity present in neocortical neurons in vivo, we
have combined computational models with whole-cell recordings using the dynamic-clamp …

Impact of network activity on the integrative properties of neocortical pyramidal neurons in vivo

A Destexhe, D Paré - Journal of neurophysiology, 1999 - journals.physiology.org
… 37 Paré D., Lang EJ, Destexhe A.Inhibitory control of somatic and dendritic sodium
spikes in neocortical pyramidal neurons in vivo: an intracellular and computational study.…

Spatiotemporal analysis of local field potentials and unit discharges in cat cerebral cortex during natural wake and sleep states

A Destexhe, D Contreras, M Steriade - Journal of Neuroscience, 1999 - Soc Neuroscience
The electroencephalogram displays various oscillation patterns during wake and sleep
states, but their spatiotemporal distribution is not completely known. Local field potentials (LFPs) …

[PDF][PDF] Kinetic models of synaptic transmission

A Destexhe, ZF Mainen, TJ Sejnowski - Methods in neuronal modeling, 1998 - csc.kth.se
The remarkably successful quantitative description of the action potential introduced by
Hodgkin and Huxley 1952 is still widely used over 40 years since its introduction. The classical …

Mechanisms underlying the synchronizing action of corticothalamic feedback through inhibition of thalamic relay cells

A Destexhe, D Contreras… - Journal of …, 1998 - journals.physiology.org
Destexhe, Alain, Diego Contreras, and Mircea Steriade. Mechanisms underlying the
synchronizing action of corticothalamic feedback through inhibition of thalamic relay cells. J. …

[BOOK][B] Rwanda and genocide in the twentieth century

A Destexhe - 1995 - books.google.com
In this slim, passionately argued volume-first published to great acclaim in France and
considerably updated during the translation process-a deeply involved witness of the massacres …